{"id":"6c43df73c02e","type":"article","url":"https://hartvaat.nl/2016/07/01/bewegingsadvies-als-behandeling-van-prehypertensie-en-hypertensie-bij-jongvolwas/","title":"Bewegingsadvies als behandeling van prehypertensie en hypertensie bij jongvolwassenen: meta-analyse","title_en":"Will Exercise Advice Be Sufficient for Treatment of Young Adults With Prehypertension and Hypertension? A Systematic Review and Meta-Analysis.","category":"hypertensie","category_label":"Hypertensie","professions":["cardioloog","huisarts"],"tags":["bloeddrukbehandeling","vrouwen","zwangerschap-hart"],"journal":"Hypertension (Dallas, Tex. : 1979)","doi":"10.1161/HYPERTENSIONAHA.116.07431","source_url":"https://doi.org/10.1161/HYPERTENSIONAHA.116.07431","authors":["Wilby Williamson","Charlie Foster","Hamish Reid","Paul Kelly","Adam James Lewandowski","Henry Boardman","Nia Roberts","David McCartney","Odaro Huckstep","Julia Newton","Helen Dawes","Stephen Gerry","Paul Leeson"],"significance":6,"published":"2016-07-01","source_date":"2016-07-01","image":"","kennis":["https://hartvaat.nl/kennis/hypertensie/hypertensie-en-ckd/","https://hartvaat.nl/kennis/nierziekte/kdigo-richtlijn-ckd-2024/"],"congress":"","summary_en":"This systematic review and meta-analysis examined whether exercise advice alone is sufficient for treating prehypertension and hypertension in young adults, evaluating the effectiveness of lifestyle modification without pharmacotherapy in this demographic.","created":"2026-07-03T10:26:11Z","updated":"2026-07-03T18:38:25Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Systematische review en meta-analyse die onderzocht of bewegingsadvies alleen voldoende is voor de behandeling van prehypertensie en hypertensie bij jongvolwassenen. Relevant voor niet-farmacologische eerste-stapstherapie.","abstract_original":"Previous studies report benefits of exercise for blood pressure control in middle age and older adults, but longer-term effectiveness in younger adults is not well established. We performed a systematic review and meta-analysis of published randomized control trials with meta-regression of potential effect modifiers. An information specialist completed a comprehensive search of available data sources, including studies published up to June 2015. Authors applied strict inclusion and exclusion criteria to screen 9524 titles. Eligible studies recruited younger adults with a cardiovascular risk factor (with at least 25% of cohort aged 18-40 years); the intervention had a defined physical activity strategy and reported blood pressure as primary or secondary outcome. Meta-analysis included 14 studies randomizing 3614 participants, mean age 42.2±6.3 (SD) years. At 3 to 6 months, exercise was associated with a reduction in systolic blood pressure of -4.40 mm Hg (95% confidence interval, -5.78 to -3.01) and in diastolic blood pressure of -4.17 mm Hg (95% confidence interval, -5.42 to -2.93). Intervention effect was not significantly influenced by baseline blood pressure, body weight, or subsequent weight loss. Observed intervention effect was lost after 12 months of follow-up with no reported benefit over control, mean difference in systolic blood pressure -1.02 mm Hg (95% confidence interval, -2.34 to 0.29), and in diastolic blood pressure -0.91 mm Hg (95% confidence interval, -1.85 to 0.02). Current exercise guidance provided to reduce blood pressure in younger adults is unlikely to benefit long-term cardiovascular risk. There is need for continued research to improve age-specific strategies and recommendations for hypertension prevention and management in young adults."}