{"id":"d736dc3f974f","type":"article","url":"https://hartvaat.nl/2016/11/29/bmi-en-nauwkeurigheid-van-nt-probnp-en-bnp-voor-diagnose-van-acuut-hartfalen/","title":"BMI en nauwkeurigheid van NT-proBNP en BNP voor diagnose van acuut hartfalen","title_en":"Impact of Body Mass Index on the Accuracy of N-Terminal Pro-Brain Natriuretic Peptide and Brain Natriuretic Peptide for Predicting Outcomes in Patients With Chronic Heart Failure and Reduced Ejection Fraction: Insights From the PARADIGM-HF Study (Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure Trial).","category":"hartfalen","category_label":"Hartfalen","professions":["cardioloog","huisarts","internist"],"tags":["acuut-hartfalen","nt-probnp","obesitas"],"journal":"Circulation","doi":"10.1161/CIRCULATIONAHA.116.024976","source_url":"https://doi.org/10.1161/CIRCULATIONAHA.116.024976","authors":["Wilson Nadruz","Brian L Claggett","John J McMurray","Milton Packer","Michael R Zile","Jean L Rouleau","Akshay S Desai","Karl Swedberg","Martin Lefkowitz","Victor C Shi","Margaret F Prescott","Scott D Solomon"],"significance":6,"published":"2016-11-29","source_date":"2016-11-29","image":"","kennis":["https://hartvaat.nl/kennis/hartfalen/diagnose-hartfalen-stappenplan/","https://hartvaat.nl/kennis/hartfalen/bnp-en-nt-probnp/"],"congress":"","summary_en":"This study showed that BMI significantly impacts the diagnostic accuracy of natriuretic peptides for acute heart failure, with obese patients having lower BNP and NT-proBNP levels at equivalent disease severity, requiring adjusted diagnostic thresholds.","created":"2026-07-03T10:26:26Z","updated":"2026-07-03T13:25:45Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Studie naar de invloed van BMI op de diagnostische nauwkeurigheid van natriuretische peptiden (NT-proBNP en BNP) bij acuut hartfalen. Relevant voor de interpretatie bij obese patiënten.","abstract_original":""}