{"id":"3401cad6836c","type":"article","url":"https://hartvaat.nl/2016/12/06/dalcetrapib-wijzigt-de-relatie-tussen-hdl-cholesterol-en-crp/","title":"Dalcetrapib wijzigt de relatie tussen HDL-cholesterol en CRP","title_en":"Treatment With Dalcetrapib Modifies the Relationship Between High-Density Lipoprotein Cholesterol and C-Reactive Protein.","category":"cholesterol","category_label":"Cholesterol","professions":["cardioloog","internist"],"tags":["cetp-remmers","ezetimibe","hdl-cholesterol","ldl-cholesterol","obicetrapib","pcsk9-remmers","statines"],"journal":"Journal of the American College of Cardiology","doi":"10.1016/j.jacc.2016.09.932","source_url":"https://doi.org/10.1016/j.jacc.2016.09.932","authors":["Reynaria Pitts","Elise Gunzburger","Christie M Ballantyne","Philip J Barter","David Kallend","Lawrence A Leiter","Eran Leitersdorf","John J V McMurray","Stephen J Nicholls","Eric J Niesor","Anders G Olsson","Prediman K Shah","Jean-Claude Tardif","John Kittelson","Gregory G Schwartz"],"significance":5,"published":"2016-12-06","source_date":"2016-12-06","image":"","kennis":["https://hartvaat.nl/kennis/lipiden/hdl-functie-en-reverse-cholesterol/"],"congress":"","summary_en":"This analysis showed that dalcetrapib (a CETP modulator) modifies the relationship between HDL cholesterol and CRP, suggesting that HDL-inflammation interaction may explain the variable cardiovascular effects of CETP inhibition.","created":"2026-07-03T10:26:27Z","updated":"2026-07-03T13:25:46Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Analyse die aantoont dat behandeling met dalcetrapib (CETP-remmer) de relatie tussen HDL-cholesterol en ontstekingsmarker CRP wijzigt. Inzicht in de complexe biologie van HDL-verhoging.","abstract_original":""}