{"id":"40faefc15347","type":"article","url":"https://hartvaat.nl/2017/04/01/beperkte-chirurgische-linkeratriumablatie-bij-af-effectief-maar-vermindert-la-fu/","title":"Beperkte chirurgische linkeratriumablatie bij AF: effectief maar vermindert LA-functie","title_en":"Limited left atrial surgical ablation effectively treats atrial fibrillation but decreases left atrial function.","category":"atriumfibrilleren","category_label":"Atriumfibrilleren","professions":["cardioloog"],"tags":["acuut-hartfalen"],"journal":"Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology","doi":"10.1093/europace/euw106","source_url":"https://doi.org/10.1093/europace/euw106","authors":["Marieke G Compier","Laurens F Tops","Jerry Braun","Katja Zeppenfeld","Robert J Klautz","Martin J Schalij","Serge A Trines"],"significance":5,"published":"2017-04-01","source_date":"2017-04-01","image":"","kennis":[],"congress":"","summary_en":"This study showed that limited surgical ablation of the left atrium effectively treats AF but impairs LA contractile function, highlighting the trade-off between rhythm control and atrial mechanical consequences.","created":"2026-07-03T10:26:38Z","updated":"2026-07-03T18:38:32Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Studie die aantoont dat beperkte chirurgische ablatie van het linker atrium effectief AF behandelt maar de linkeratriumfunctie vermindert. Balans tussen ritmevoordeel en atriumfunctieverlies.","abstract_original":"AIMS: Limited left atrial (LA) surgical ablation with bipolar radiofrequency is considered to be an effective procedure for treatment of atrial fibrillation (AF). We studied whether limited LA surgical ablation concomitant to cardiac surgery is able to maintain LA function. METHODS AND RESULTS: Thirty-six consecutive patients (age 66 ± 12 years, 53% male, 78% persistent AF) scheduled for valve surgery and/or coronary revascularization and concomitant LA surgical ablation were included. Epicardial pulmonary vein isolation (PVI) and additional endo-epicardial lines were performed using bipolar radiofrequency. An age- and gender-matched control group (n = 36, age 66 ± 9 years, 69% male, 81% paroxysmal AF) was selected from patients undergoing concomitant epicardial PVI only. Left atrial dimensions and function were assessed on two-dimensional echocardiography preoperatively and at 3- and 12-month follow-up. Sinus rhythm (SR) maintenance was 67% for limited LA ablation and 81% for PVI at 1-year follow-up (P = 0.18). Left atrial volume decreased from 72 ± 21 to 50 ± 14 mL (31%, P < 0.01) after limited LA ablation and from 65 ± 23 to 56 ± 20 mL (14%, P < 0.01) after PVI. Atrial transport function was restored in 54% of patients in SR after limited LA ablation compared with 100% of patients in SR after PVI. Atrial strain and contraction parameters (LA ejection fraction, A-wave velocity, reservoir function, and strain rate) significantly decreased after limited LA ablation. After PVI, strain and contraction parameters remained unchanged. CONCLUSION: Even limited LA ablation decreased LA volume, contraction, transport function, and compliance, indicating both reverse remodelling combined with significant functional deterioration. In contrast, surgical PVI decreased LA volume while function remained unchanged."}