{"id":"1147b78d60d7","type":"article","url":"https://hartvaat.nl/2018/01/01/linkeratriumvolume-voorspelt-af-recidief-na-radiofrequentieablatie-meta-analyse/","title":"Linkeratriumvolume voorspelt AF-recidief na radiofrequentieablatie: meta-analyse","title_en":"Left atrial volume predicts atrial fibrillation recurrence after radiofrequency ablation: a meta-analysis.","category":"atriumfibrilleren","category_label":"Atriumfibrilleren","professions":["cardioloog"],"tags":[],"journal":"Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology","doi":"10.1093/europace/eux013","source_url":"https://doi.org/10.1093/europace/eux013","authors":["Augustine Njoku","Munish Kannabhiran","Rishi Arora","Pratap Reddy","Rakesh Gopinathannair","Dhanunjaya Lakkireddy","Paari Dominic"],"significance":6,"published":"2018-01-01","source_date":"2018-01-01","image":"","kennis":[],"congress":"","summary_en":"This meta-analysis confirmed that left atrial volume (rather than diameter alone) independently predicts AF recurrence after radiofrequency ablation, supporting volumetric assessment for patient selection.","created":"2026-07-03T10:27:04Z","updated":"2026-07-03T13:26:21Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Meta-analyse die bevestigt dat linkeratriumvolume een onafhankelijke voorspeller is van AF-recidief na radiofrequentieablatie.","abstract_original":"AIMS: Left atrial (LA) diameter is a predictor of atrial fibrillation (AF) recurrence following radiofrequency catheter ablation (RFA). However, LA volume (LAV) is more accurate in assessing LA size. Studies evaluating LAV as a predictor of AF recurrence are contradictory; therefore, we performed a meta-analysis to assess whether LAV is an independent predictor of AF recurrence following RFA. METHODS AND RESULTS: All studies reporting LAV/LAV index (LAVi) as a predictor of AF recurrence following RFA were included. For studies reporting mean LAV/ LAVi in patients with and without AF recurrence, standard difference in means (SDM) and standard errors were calculated, and combined using meta-analytical techniques. For studies reporting adjusted odds ratio (OR) for AF recurrence based on LAV/LAVi, log ORs were combined using generic inverse variance. Twenty one studies (3822 subjects) were included. Meta-analysis of 11 studies (1559 subjects) reporting LAV, showed that patients with AF recurrence had a higher mean LA volume compared to patients with no recurrence (SDM 0.801; CI 0.387-1.216). Data from 9 studies (1425 subjects) comparing LAVi showed that, patients with AF recurrence had a higher mean LAVi compared to patients with no recurrence (SDM-0.596; CI 0.305-0.888). Thirteen studies (2886 patients) reporting ORs for AF recurrence based on LAV/ LAVi, showed that LAV/LAVi was independently predictive of AF recurrence post-RFA (OR-1.032, CI- 1.012-1.052). CONCLUSIONS: Patients with AF recurrence following RFA have a higher mean LAV/LAVi compared to patients with no recurrence. Large LAV/LAVi increases the odds of AF recurrence post RFA."}