{"id":"394930486db6","type":"article","url":"https://hartvaat.nl/2018/01/16/intraveneus-fentanyl-en-ticagrelorabsorptie-bij-pci/","title":"Intraveneus fentanyl en ticagrelorabsorptie bij PCI","title_en":"Effect of Intravenous Fentanyl on Ticagrelor Absorption and Platelet Inhibition Among Patients Undergoing Percutaneous Coronary Intervention: The PACIFY Randomized Clinical Trial (Platelet Aggregation With Ticagrelor Inhibition and Fentanyl).","category":"algemeen","category_label":"Algemeen","professions":["apotheker","cardioloog"],"tags":[],"journal":"Circulation","doi":"10.1161/CIRCULATIONAHA.117.031678","source_url":"https://doi.org/10.1161/CIRCULATIONAHA.117.031678","authors":["John W McEvoy","Khalil Ibrahim","Thomas S Kickler","William A Clarke","Rani K Hasan","Matthew J Czarny","Ali R Keramati","Rakesh R Goli","Travis P Gratton","Jeffrey A Brinker","Matthews Chacko","Chao-Wei Hwang","Peter V Johnston","Julie M Miller","Jeffrey C Trost","William R Herzog","Roger S Blumenthal","David R Thiemann","Jon R Resar","Steven P Schulman"],"significance":6,"published":"2018-01-16","source_date":"2018-01-16","image":"","kennis":["https://hartvaat.nl/kennis/coronairlijden/stemi/"],"congress":"","summary_en":"This study showed that intravenous fentanyl delays ticagrelor absorption and attenuates platelet inhibition during PCI, adding to the evidence for opioid-antiplatelet drug interactions in the catheterization laboratory.","created":"2026-07-03T10:27:06Z","updated":"2026-07-03T13:26:22Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Studie die het effect van IV fentanyl op de absorptie en plaatjesremming van ticagrelor onderzocht tijdens PCI. Opioïde-antiplaatjesinteractie analoog aan het morfineprobleem.","abstract_original":""}