{"id":"03847b439209","type":"article","url":"https://hartvaat.nl/2018/05/08/spontane-coronaire-arterie-dissectie-aha-scientific-statement/","title":"Spontane coronaire arterie dissectie: AHA scientific statement","title_en":"Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association.","category":"algemeen","category_label":"Algemeen","professions":["cardioloog"],"tags":["spontane-coronairdissectie"],"journal":"Circulation","doi":"10.1161/CIR.0000000000000564","source_url":"https://doi.org/10.1161/CIR.0000000000000564","authors":["Sharonne N Hayes","Esther S H Kim","Jacqueline Saw","David Adlam","Cynthia Arslanian-Engoren","Katherine E Economy","Santhi K Ganesh","Rajiv Gulati","Mark E Lindsay","Jennifer H Mieres","Sahar Naderi","Svati Shah","David E Thaler","Marysia S Tweet","Malissa J Wood"],"significance":8,"published":"2018-05-08","source_date":"2018-05-08","image":"","kennis":["https://hartvaat.nl/kennis/coronairlijden/spontane-coronaire-arterie-dissectie/"],"congress":"","summary_en":"This AHA scientific statement provided the first comprehensive review of spontaneous coronary artery dissection (SCAD), covering epidemiology, pathophysiology, diagnosis, and management of this increasingly recognized cause of acute coronary syndrome, particularly in young women.","created":"2026-07-03T10:27:17Z","updated":"2026-07-03T13:26:32Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"AHA scientific statement over de huidige kennis van spontane coronaire arterie dissectie (SCAD). Eerste uitgebreide overzicht van deze steeds vaker herkende oorzaak van acuut MI bij jonge vrouwen.","abstract_original":"Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, particularly among young women and individuals with few conventional atherosclerotic risk factors. Patient-initiated research has spurred increased awareness of SCAD, and improved diagnostic capabilities and findings from large case series have led to changes in approaches to initial and long-term management and increasing evidence that SCAD not only is more common than previously believed but also must be evaluated and treated differently from atherosclerotic myocardial infarction. High rates of recurrent SCAD; its association with female sex, pregnancy, and physical and emotional stress triggers; and concurrent systemic arteriopathies, particularly fibromuscular dysplasia, highlight the differences in clinical characteristics of SCAD compared with atherosclerotic disease. Recent insights into the causes of, clinical course of, treatment options for, outcomes of, and associated conditions of SCAD and the many persistent knowledge gaps are presented."}