{"id":"76ab68c1abb7","type":"article","url":"https://hartvaat.nl/2018/06/01/interarmbloeddrukverschil-en-beroerte-ipd-meta-analyse/","title":"Interarmbloeddrukverschil en beroerte: IPD meta-analyse","title_en":"Simultaneously Measured Interarm Blood Pressure Difference and Stroke: An Individual Participants Data Meta-Analysis.","category":"hypertensie","category_label":"Hypertensie","professions":["cardioloog","huisarts"],"tags":["perifeer-vaatlijden"],"journal":"Hypertension (Dallas, Tex. : 1979)","doi":"10.1161/HYPERTENSIONAHA.118.10923","source_url":"https://doi.org/10.1161/HYPERTENSIONAHA.118.10923","authors":["Hirofumi Tomiyama","Toshiaki Ohkuma","Toshiharu Ninomiya","Chisa Mastumoto","Kazuomi Kario","Satoshi Hoshide","Yoshikuni Kita","Toyoshi Inoguchi","Yasutaka Maeda","Katsuhiko Kohara","Yasuharu Tabara","Motoyuki Nakamura","Takayoshi Ohkubo","Hirotaka Watada","Masanori Munakata","Mitsuru Ohishi","Norihisa Ito","Michinari Nakamura","Tetsuo Shoji","Charalambos Vlachopoulos","Akira Yamashina"],"significance":6,"published":"2018-06-01","source_date":"2018-06-01","image":"","kennis":[],"congress":"","summary_en":"This individual patient data meta-analysis showed that simultaneously measured interarm blood pressure difference predicts stroke risk, supporting routine bilateral measurement as a simple screening tool for vascular asymmetry.","created":"2026-07-03T10:27:19Z","updated":"2026-07-03T13:26:34Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Individuele patiëntdata meta-analyse naar het verband tussen simultaan gemeten interarmbloeddrukverschil en beroerterisico. Eenvoudige klinische marker voor vasculair risico.","abstract_original":"We conducted individual participant data meta-analysis to examine the validity of interarm blood pressure difference in simultaneous measurement as a marker to identify subjects with ankle-brachial pressure index <0.90 and to predict future cardiovascular events. We collected individual participant data on 13 317 Japanese subjects from 10 cohorts (general population-based cohorts, cohorts of patients with past history of cardiovascular events, and those with cardiovascular risk factors). Binary logistic regression analysis with adjustments identified interarm blood pressure difference >5 mm Hg as being associated with a significant odds ratio for the presence of ankle-brachial pressure index <0.90 (odds ratio, 2.19; 95% confidence interval, 1.60-3.03; P<0.01). Among 11 726 subjects without a past history of cardiovascular disease, 249 developed stroke during the average follow-up period of 7.4 years. Interarm blood pressure difference >15 mm Hg was associated with a significant Cox stratified adjusted hazard ratio for subsequent stroke (hazard ratio, 2.42; 95% confidence interval, 1.27-4.60; P<0.01). Therefore, interarm blood pressure differences, measured simultaneously in both arms, may be associated with vascular damage in the systemic arterial tree. These differences may be useful for identifying subjects with an ankle-brachial pressure index of <0.90 in the overall study population, and also a reliable predictor of future stroke in subjects without a past history of cardiovascular disease. These findings support the recommendation to measure blood pressure in both arms at the first visit."}