# Mediterraan dieet verbetert systolische bloeddruk en arteriële stijfheid bij ouderen

*geplaatst 2019-03-01 · Hypertensie · Hypertension (Dallas, Tex. : 1979) · doi 10.1161/HYPERTENSIONAHA.118.12259 · https://hartvaat.nl/2019/03/01/mediterraan-dieet-verbetert-systolische-bloeddruk-en-arteriele-stijfheid-bij-oud/*

Studie die aantoont dat een mediterraan dieet de systolische bloeddruk en arteriële stijfheid verbetert bij oudere volwassenen.

## English: Mediterranean-Style Diet Improves Systolic Blood Pressure and Arterial Stiffness in Older Adults.

This study demonstrated that a Mediterranean-style diet tailored for older adults improves systolic blood pressure and arterial stiffness, providing dietary evidence specifically for the elderly hypertensive population.

## Abstract (original, from the publication)

We aimed to determine the effect of a Mediterranean-style diet, tailored to meet dietary recommendations for older adults, on blood pressure and arterial stiffness. In 12 months, randomized controlled trial (NU-AGE [New Dietary Strategies Addressing the Specific Needs of Elderly Population for Healthy Aging in Europe]), blood pressure was measured in 1294 healthy participants, aged 65 to 79 years, recruited from 5 European centers, and arterial stiffness in a subset of 225 participants. The intervention group received individually tailored standardized dietary advice and commercially available foods to increase adherence to a Mediterranean diet. The control group continued on their habitual diet and was provided with current national dietary guidance. In the 1142 participants who completed the trial (88.2%), after 1 year the intervention resulted in a significant reduction in systolic blood pressure (-5.5 mm Hg; 95% CI, -10.7 to -0.4; P=0.03), which was evident in males (-9.2 mm Hg, P=0.02) but not females (-3.1 mm Hg, P=0.37). The -1.7 mm Hg (95% CI, -4.3 to 0.9) decrease in diastolic pressure after intervention did not reach statistical significance. In a subset (n=225), augmentation index, a measure of arterial stiffness, was improved following intervention (-12.4; 95% CI, -24.4 to -0.5; P=0.04) with no change in pulse wave velocity. The intervention also resulted in an increase in 24-hour urinary potassium (8.8 mmol/L; 95% CI, 0.7-16.9; P=0.03) and in male participants (52%) a reduction in pulse pressure (-6.1 mm Hg; 95% CI, -12.0 to -0.2; P=0.04) and 24-hour urinary sodium (-27.1 mmol/L; 95% CI, -53.3 to -1.0; P=0.04). In conclusion, a Mediterranean-style diet is effective in improving cardiovascular health with clinically relevant reductions in blood pressure and arterial stiffness. Clinical Trial Registration- URL: http://www.clinicialtrials.gov . Unique identifier: NCT01754012.

Auteurs: Amy Jennings, Agnes M Berendsen, Lisette C P G M de Groot, Edith J M Feskens, Anna Brzozowska, Ewa Sicinska, Barbara Pietruszka, Nathalie Meunier, Elodie Caumon, Corinne Malpuech-Brugère, Aurelia Santoro, Rita Ostan, Claudio Franceschi, Rachel Gillings, Colette M O' Neill, Sue J Fairweather-Tait, Anne-Marie Minihane, Aedín Cassidy

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Bron: Hypertension (Dallas, Tex. : 1979), https://doi.org/10.1161/HYPERTENSIONAHA.118.12259. Bijgewerkt 2026-07-03T18:38:42Z. Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.