{"id":"3c083f8094ce","type":"article","url":"https://hartvaat.nl/2019/06/18/2018-aha-acc-cholesterolrichtlijn-executive-summary/","title":"2018 AHA/ACC cholesterolrichtlijn: executive summary","title_en":"2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.","category":"cholesterol","category_label":"Cholesterol","professions":["apotheker","cardioloog","huisarts","internist"],"tags":["ezetimibe","ldl-cholesterol","niet-statine-therapie","pcsk9-remmers","statines"],"journal":"Circulation","doi":"10.1161/CIR.0000000000000624","source_url":"https://doi.org/10.1161/CIR.0000000000000624","authors":["Scott M Grundy","Neil J Stone","Alison L Bailey","Craig Beam","Kim K Birtcher","Roger S Blumenthal","Lynne T Braun","Sarah de Ferranti","Joseph Faiella-Tommasino","Daniel E Forman","Ronald Goldberg","Paul A Heidenreich","Mark A Hlatky","Daniel W Jones","Donald Lloyd-Jones","Nuria Lopez-Pajares","Chiadi E Ndumele","Carl E Orringer","Carmen A Peralta","Joseph J Saseen","Sidney C Smith","Laurence Sperling","Salim S Virani","Joseph Yeboah"],"significance":10,"published":"2019-06-18","source_date":"2019-06-18","image":"","kennis":["https://hartvaat.nl/kennis/lipiden/ldl-cholesterol-mechanisme/","https://hartvaat.nl/kennis/lipiden/esc-richtlijn-dyslipidemie-2019/"],"congress":"","summary_en":"The 2018 AHA/ACC cholesterol guideline executive summary introduced risk enhancers, coronary artery calcium scoring for shared decision-making, and LDL-cholesterol thresholds for escalating therapy to PCSK9 inhibitors. The guideline shifted the paradigm from fixed-dose statin therapy toward personalized, risk-based LDL management.","created":"2026-07-03T10:27:59Z","updated":"2026-07-03T13:27:11Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Executive summary van de 2018 AHA/ACC cholesterolrichtlijn met geactualiseerde aanbevelingen voor LDL-management inclusief PCSK9-remmers en risicoversterkers.","abstract_original":""}