{"id":"6cb3846975d4","type":"article","url":"https://hartvaat.nl/2020/11/01/inspanningsinterventie-verbetert-qol-na-mi-bij-ouderen-gerandomiseerde-trial/","title":"Inspanningsinterventie verbetert QoL na MI bij ouderen: gerandomiseerde trial","title_en":"Exercise intervention improves quality of life in older adults after myocardial infarction: randomised clinical trial.","category":"algemeen","category_label":"Algemeen","professions":["cardioloog","huisarts"],"tags":[],"journal":"Heart (British Cardiac Society)","doi":"10.1136/heartjnl-2019-316349","source_url":"https://doi.org/10.1136/heartjnl-2019-316349","authors":["Gianluca Campo","Elisabetta Tonet","Giorgio Chiaranda","Gianluigi Sella","Elisa Maietti","Giulia Bugani","Francesco Vitali","Matteo Serenelli","Gianni Mazzoni","Rossella Ruggiero","Giovanni Villani","Simone Biscaglia","Rita Pavasini","Andrea Rubboli","Roberta Campana","Serena Caglioni","Stefano Volpato","Jonathan Myers","Giovanni Grazzi"],"significance":6,"published":"2020-11-01","source_date":"2020-11-01","image":"","kennis":["https://hartvaat.nl/kennis/coronairlijden/revalidatie-na-hartinfarct/","https://hartvaat.nl/kennis/cardiometabool/cardiometabool-spreekuur/"],"congress":"","summary_en":"This randomized trial showed that an early, tailored, low-cost exercise intervention improves quality of life in older patients after myocardial infarction, supporting accessible rehabilitation for the elderly MI population.","created":"2026-07-03T10:28:51Z","updated":"2026-07-03T13:28:00Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Gerandomiseerde trial die aantoont dat inspanningsinterventie de kwaliteit van leven verbetert bij oudere MI-patiënten.","abstract_original":"OBJECTIVE: To establish the benefits of an early, tailored and low-cost exercise intervention in older patients hospitalised for acute coronary syndrome (ACS). METHODS: The study was a multicentre, randomised assessment of an exercise intervention in patients with ACS ≥70 years with reduced physical performance (as defined by the short physical performance battery (SPPB), value 4-9). The exercise intervention included four supervised sessions (1, 2, 3, 4 months after discharge) and home-based exercises. The control group attended a health education programme only. The outcomes were the 6-month and 1-year effects on physical performance, daily activities, anxiety/depression and quality of life. Finally, 1-year occurrence of adverse events was recorded. RESULTS: Overall, 235 patients with ACS (median age 76 (73-81) years) were randomised 1 month after ACS. Exercise and control groups were well balanced. Exercise intervention improved 6-month and 1-year grip strength and gait speed. Exercise intervention was associated with a better quality of life (as measured by EuroQol-visual analogue scale at 6 months 80 (70-90) vs 70 (50-80) points, p<0.001 and at 1 year 75 (70-87) vs 65 (50-80) points, p<0.001) and with a reduced perception of anxiety and/or depression (6 months: 21% vs 42%, p=0.001; 1 year 32% vs 47%, p=0.03). The occurrence of cardiac death and hospitalisation for cardiac cause was lower in the intervention group (7.5% vs 17%, p=0.04). CONCLUSIONS: The proposed early, tailored, low-cost exercise intervention improves mobility, daily activities, quality of life and outcomes in older patients with ACS. Larger studies are needed to confirm the clinical benefit. TRIAL REGISTRATION NUMBER: NCT03021044."}