{"id":"0b312ce7c9b0","type":"article","url":"https://hartvaat.nl/2021/04/01/ventriculaire-aritmie-of-overlijden-na-stemi-versus-takotsubo/","title":"Ventriculaire aritmie of overlijden na STEMI versus takotsubo","title_en":"Risk of in-hospital life-threatening ventricular arrhythmia or death after ST-elevation myocardial infarction vs. the Takotsubo syndrome.","category":"algemeen","category_label":"Algemeen","professions":["cardioloog"],"tags":["ventriculaire-tachycardie"],"journal":"ESC heart failure","doi":"10.1002/ehf2.13208","source_url":"https://doi.org/10.1002/ehf2.13208","authors":["Rickard Zeijlon","Jasmina Chamat","Israa Enabtawi","Sandeep Jha","Mohammed Munir Mohammed","Johan Wågerman","Vina Le","Aaron Shekka Espinosa","Erik Nyman","Elmir Omerovic","Björn Redfors"],"significance":5,"published":"2021-04-01","source_date":"2021-04-01","image":"","kennis":["https://hartvaat.nl/kennis/ritmestoornissen/sport-en-ritmestoornissen/"],"congress":"","summary_en":"This study compared the risk of life-threatening ventricular arrhythmias between STEMI and Takotsubo syndrome, showing that arrhythmic risk is lower in Takotsubo despite similar acute presentation.","created":"2026-07-03T10:29:07Z","updated":"2026-07-03T13:28:15Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Vergelijking van het risico op levensbedreigende ventriculaire aritmie of overlijden bij STEMI versus takotsubo.","abstract_original":"AIMS: The risk of life-threatening ventricular arrhythmias (LTVA) has been reported to be lower in Takotsubo syndrome (TS) compared with ST-elevation myocardial infarction (STEMI). However, the extent to which these differences relate to the fact that most patients with TS are women (who have a lower risk of LTVA) and a relatively larger proportion of patients with STEMI are men is incompletely understood. We aimed to investigate the risk of LTVA or death in sex-matched and age-matched patients with TS, anterior STEMI, and non-anterior STEMI. METHODS AND RESULTS: We systematically reviewed the charts of all patients with TS who were treated at Sahlgrenska University Hospital (Gothenburg, Sweden) between 2008 and 2019. A total of 155 patients with confirmed TS (according to the European Society of Cardiology diagnostic criteria for TS) were sex-matched and age-matched 1:1:1 to patients with anterior and non-anterior STEMI. Baseline characteristics and in-hospital outcomes were recorded directly from the patient charts for all patients, and all admission electrocardiographs were analysed. The primary outcome was the composite of death or LTVA [defined as sustained ventricular tachycardia (>30 s) or ventricular fibrillation] within 72 h. The risk of LTVA or death within 72 h after admission was considerably lower in TS (2.6%) vs. anterior STEMI (14%; P = 0.002) and non-anterior STEMI (9.0%; P = 0.02), despite similar or greater risks of acute heart failure, and similar risks of cardiogenic shock. Compared with STEMI, TS was associated with a lower risk of sustained and non-sustained ventricular tachycardia and ventricular fibrillation. CONCLUSIONS: In a predominantly female age-matched and sex-matched cohort of patients with TS, anterior STEMI, and non-anterior STEMI, the adjusted risk of in-hospital LTVA or death was considerably lower in TS compared with STEMI, despite similar or greater risk of acute heart failure and similar risk of cardiogenic shock."}