{"id":"987882a757d2","type":"article","url":"https://hartvaat.nl/2022/07/26/chinees-hartgezond-dieet-verlaagt-bloeddruk-effectief-gerandomiseerde-trial/","title":"Chinees hartgezond dieet verlaagt bloeddruk effectief: gerandomiseerde trial","title_en":"Effects of Cuisine-Based Chinese Heart-Healthy Diet in Lowering Blood Pressure Among Adults in China: Multicenter, Single-Blind, Randomized, Parallel Controlled Feeding Trial.","category":"hypertensie","category_label":"Hypertensie","professions":["cardioloog","huisarts","internist"],"tags":[],"journal":"Circulation","doi":"10.1161/CIRCULATIONAHA.122.059045","source_url":"https://doi.org/10.1161/CIRCULATIONAHA.122.059045","authors":["Yanfang Wang","Lin Feng","Guo Zeng","Huilian Zhu","Jianqin Sun","Pei Gao","Jihong Yuan","Xi Lan","Shuyi Li","Yanfang Zhao","Xiayan Chen","Hongli Dong","Si Chen","Zhen Li","Yidan Zhu","Ming Li","Xiang Li","Zhenquan Yang","Huijuan Li","Hai Fang","Gaoqiang Xie","Pao-Hwa Lin","Junshi Chen","Yangfeng Wu"],"significance":7,"published":"2022-07-26","source_date":"2022-07-26","image":"","kennis":["https://hartvaat.nl/kennis/preventie/leefstijladvisering-cardiologie/"],"congress":"","summary_en":"This multicenter trial developed and tested an evidence-based heart-healthy diet adapted to Chinese cuisine that significantly lowered blood pressure. The culturally tailored dietary approach addresses the cardiovascular needs of the world's largest cuisine population.","created":"2026-07-03T10:29:50Z","updated":"2026-07-03T13:28:57Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Multicenter trial ontwikkelde en testte een evidence-based hartgezond dieet aangepast aan de Chinese keuken. Het dieet verlaagde de systolische bloeddruk met 10 mmHg meer dan het controledieet, vergelijkbaar met het DASH-dieet. Dit toont dat cultuurspecifieke dieetinterventies effectief zijn.","abstract_original":"BACKGROUND: More than one-fifth of the world's population consumes Chinese cuisines regularly, but no evidence-based healthy diets fitting the Chinese food culture are available for implementation. METHODS: A multicenter, patient- and outcome assessor-blind, randomized feeding trial was conducted among 265 participants with 130 to 159 mm Hg baseline systolic blood pressure (SBP) for 4 major Chinese cuisines (Shangdong, Huaiyang, Cantonese, Szechuan). After a 7-day run-in period on a control diet matching the usual local diets, participants were randomized to continue with the control diet or the cuisine-based Chinese heart-healthy diet for another 28 days. The primary outcome was SBP, and secondary outcomes included diastolic blood pressure and food preference score. Linear regression models were used to estimate the intervention effects and adjustments for the center. The incremental cost per 1 mm Hg reduction in SBP was also calculated. RESULTS: A total of 265 participants were randomized (135 on the Chinese heart-healthy diet and 130 on the control diet), with 52% women, mean age of 56.5±9.8 years, and mean SBP and diastolic blood pressure of 139.4±8.3 and 88.1±8.0 mm Hg, respectively, at baseline. The change in SBP and diastolic blood pressure from baseline to the end of the study in the control group was -5.0 (95% CI, -6.5 to -3.5) mm Hg and -2.8 (95% CI, -3.7 to -1.9) mm Hg, respectively. The net difference of change between the 2 groups in SBP and diastolic blood pressure were -10.0 (95% CI, -12.1 to -7.9) mm Hg and -3.8 (95% CI, -5.0 to -2.5) mm Hg, respectively. The effect size did not differ among cuisines (P for interaction=0.173). The mean food preference score was 9.5 (with 10 the best preferred) at baseline, and the net change during intervention was 0.1 (95% CI, -0.1 to 0.2; P=0.558). The incremental cost-effectiveness ratio per 1 mm Hg SBP reduction was CNY 0.4 (USD 0.06) per day. No difference in the number of adverse events was found between the 2 groups (P=0.259), and none of the adverse events was associated with the intervention. CONCLUSIONS: The Chinese heart-healthy diet is effective, palatable, and cost-effective in reducing blood pressure in Chinese adults with high blood pressure, with a clinically significant effect applicable across major Chinese cuisine cultures. REGISTRATION: URL: https://www. CLINICALTRIALS: gov; Unique identifier: NCT03882645."}