{"id":"94e3c1d4f8dd","type":"article","url":"https://hartvaat.nl/2022/12/01/apotheker-geleide-telezorg-versus-poliklinische-zorg-bij-ongecontroleerde-hypert/","title":"Apotheker-geleide telezorg versus poliklinische zorg bij ongecontroleerde hypertensie","title_en":"Comparing Pharmacist-Led Telehealth Care and Clinic-Based Care for Uncontrolled High Blood Pressure: The Hyperlink 3 Pragmatic Cluster-Randomized Trial.","category":"hypertensie","category_label":"Hypertensie","professions":["apotheker","cardioloog","huisarts"],"tags":["bloeddrukbehandeling","thuisbloeddrukmeting"],"journal":"Hypertension (Dallas, Tex. : 1979)","doi":"10.1161/HYPERTENSIONAHA.122.19816","source_url":"https://doi.org/10.1161/HYPERTENSIONAHA.122.19816","authors":["Karen L Margolis","Anna R Bergdall","A Lauren Crain","Meghan M JaKa","Jeffrey P Anderson","Leif I Solberg","JoAnn Sperl-Hillen","MarySue Beran","Beverly B Green","Patricia Haugen","Christine K Norton","Amy J Kodet","Rashmi Sharma","Deepika Appana","Nicole K Trower","Pamala A Pawloski","Daniel J Rehrauer","Maria L Simmons","Zeke J McKinney","Thomas E Kottke","Jeanette Y Ziegenfuss","Rae Ann Williams","Patrick J O'Connor"],"significance":6,"published":"2022-12-01","source_date":"2022-12-01","image":"","kennis":["https://hartvaat.nl/kennis/hypertensie/hypertensie-en-ckd/","https://hartvaat.nl/kennis/hypertensie/therapietrouw-hypertensie/"],"congress":"","summary_en":"The Hyperlink 3 trial showed that pharmacist-led telehealth care achieves comparable blood pressure control to clinic-based care in uncontrolled hypertension, validating remote team-based management models.","created":"2026-07-03T10:30:06Z","updated":"2026-07-03T18:38:58Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"De Hyperlink 3 pragmatische cluster-RCT toonde dat apotheker-geleide telezorg even effectief was als poliklinische zorg bij ongecontroleerde hypertensie. Telezorg biedt een toegankelijk alternatief dat de bloeddrukcontrole kan verbeteren.","abstract_original":"BACKGROUND: A team approach is one of the most effective ways to lower blood pressure (BP) in uncontrolled hypertension, but different models for organizing team-based care have not been compared directly. METHODS: A pragmatic, cluster-randomized trial compared 2 interventions in adult patients with moderately severe hypertension (BP≥150/95 mm Hg): (1) clinic-based care using best practices and face-to-face visits with physicians and medical assistants; and (2) telehealth care using best practices and adding home BP telemonitoring with home-based care coordinated by a clinical pharmacist or nurse practitioner. The primary outcome was change in systolic BP over 12 months. Secondary outcomes were change in patient-reported outcomes over 6 months. RESULTS: Participants (N=3071 in 21 primary care clinics) were on average 60 years old, 47% male, and 19% Black. Protocol-specified follow-up within 6 weeks was 32% in clinic-based care and 27% in telehealth care. BP decreased significantly during 12 months of follow-up in both groups, from 157/92 to 139/82 mm Hg in clinic-based care patients (adjusted mean difference -18/-10 mm Hg) and 157/91 to 139/81 mm Hg in telehealth care patients (adjusted mean difference -19/-10 mm Hg), with no significant difference in systolic BP change between groups (-0.8 mm Hg [95% CI, -2.84 to 1.32]). Telehealth care patients were significantly more likely than clinic-based care patients to report frequent home BP measurement, rate their BP care highly, and report that BP care visits were convenient. CONCLUSIONS: Telehealth care that includes extended team care is an effective and safe alternative to clinic-based care for improving patient-centered care for hypertension. REGISTRATION: URL: https://www. CLINICALTRIALS: gov; Unique identifier: NCT02996565."}