# Complicaties van AF-ablatie: actueel overzicht

*geplaatst 2023-05-30 · Atriumfibrilleren · Journal of the American College of Cardiology · doi 10.1016/j.jacc.2023.03.418 · https://hartvaat.nl/2023/05/30/complicaties-van-af-ablatie-actueel-overzicht/*

Uitgebreid overzicht van proceduregebonden complicaties bij catheterablatie voor AF. De totale complicatieratio is gedaald door technologische vooruitgang, maar ernstige complicaties (tamponnade, CVA, slokdarmfistel) vereisen blijvende waakzaamheid.

## English: Procedure-Related Complications of Catheter Ablation for Atrial Fibrillation.

This comprehensive review of procedure-related complications of AF catheter ablation documented declining complication rates over time, providing current safety benchmarks and prevention strategies for the most common procedural risks.

## Abstract (original, from the publication)

BACKGROUND: Catheter ablation of atrial fibrillation (AF) is a commonly performed procedure. However, it is associated with potentially significant complications. Reported procedure-related complication rates are highly variable, depending in part on study design. OBJECTIVES: The purpose of this systematic review and pooled analysis was to determine the rate of procedure-related complications associated with catheter ablation of AF using data from randomized control trials and to assess temporal trends. METHODS: MEDLINE and EMBASE databases were searched from January 2013 to September 2022 for randomized control trials that included patients undergoing a first ablation procedure of AF using either radiofrequency or cryoballoon (PROSPERO, CRD42022370273). RESULTS: A total of 1,468 references were retrieved, of which 89 studies met inclusion criteria. A total of 15,701 patients were included in the current analysis. Overall and severe procedure-related complication rates were 4.51% (95% CI: 3.76%-5.32%) and 2.44% (95% CI: 1.98%-2.93%), respectively. Vascular complications were the most frequent type of complication (1.31%). The next most common complications were pericardial effusion/tamponade (0.78%) and stroke/transient ischemic attack (0.17%). The procedure-related complication rate during the most recent 5-year period of publication was significantly lower than during the earlier 5-year period (3.77% vs 5.31%; P = 0.043). The pooled mortality rate was stable over the 2 time periods (0.06% vs 0.05%; P = 0.892). There was no significant difference in complication rate according to pattern of AF, ablation modality, or ablation strategies beyond pulmonary vein isolation. CONCLUSIONS: Procedure-related complications and mortality rates associated with catheter ablation of AF are low and have declined in the past decade.

Auteurs: Karim Benali, Paul Khairy, Nefissa Hammache, Adrian Petzl, Antoine Da Costa, Atul Verma, Jason G Andrade, Laurent Macle

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Bron: Journal of the American College of Cardiology, https://doi.org/10.1016/j.jacc.2023.03.418. Bijgewerkt 2026-07-03T13:29:27Z. Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.