{"id":"7b3e09c52496","type":"article","url":"https://hartvaat.nl/2023/07/21/rood-vlees-cardiovasculaire-ziekte-en-diabetes-systematische-review/","title":"Rood vlees, cardiovasculaire ziekte en diabetes: systematische review","title_en":"Red meat consumption, cardiovascular diseases, and diabetes: a systematic review and meta-analysis.","category":"atriumfibrilleren","category_label":"Atriumfibrilleren","professions":["cardioloog","huisarts","internist"],"tags":["acuut-hartfalen","anemie-ckd","biomarkers-cardiovasculair","bloeddrukbehandeling","bradycardie","diabetes-en-hart","diabetes-type-1","diabetes-type-2","dyslipidemie","ezetimibe","farmaco-economie","figaro-dkd","microbioom","obesitas","ouderen","perifeer-vaatlijden","roken","slaapapneu","soul-trial","supraventriculaire-tachycardie","tirzepatide","vrouwen"],"journal":"European heart journal","doi":"10.1093/eurheartj/ehad336","source_url":"https://doi.org/10.1093/eurheartj/ehad336","authors":["Wenming Shi","Xin Huang","C Mary Schooling","Jie V Zhao"],"significance":7,"published":"2023-07-21","source_date":"2023-07-21","image":"","kennis":[],"congress":"","summary_en":"This systematic review and meta-analysis confirmed a modest but consistent association between red meat consumption and cardiovascular disease and diabetes, though the effect size was smaller than commonly assumed.","created":"2026-07-03T10:30:29Z","updated":"2026-07-03T18:39:04Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Systematische review en meta-analyse bevestigden een bescheiden maar consistent verband tussen rood vleesconsumptie en cardiovasculaire ziekte en diabetes. Bewerkt vlees toonde een sterker verband dan onbewerkt vlees. Matige consumptie met nadruk op vermindering van bewerkt vlees wordt aanbevolen.","abstract_original":"AIMS: Observational studies show inconsistent associations of red meat consumption with cardiovascular disease (CVD) and diabetes. Moreover, red meat consumption varies by sex and setting, however, whether the associations vary by sex and setting remains unclear. METHODS AND RESULTS: This systematic review and meta-analysis was conducted to summarize the evidence concerning the associations of unprocessed and processed red meat consumption with CVD and its subtypes [coronary heart disease (CHD), stroke, and heart failure], type two diabetes mellitus (T2DM), and gestational diabetes mellitus (GDM) and to assess differences by sex and setting (western vs. eastern, categorized based on dietary pattern and geographic region). Two researchers independently screened studies from PubMed, Web of Science, Embase, and the Cochrane Library for observational studies and randomized controlled trials (RCTs) published by 30 June 2022. Forty-three observational studies (N = 4 462 810, 61.7% women) for CVD and 27 observational studies (N = 1 760 774, 64.4% women) for diabetes were included. Red meat consumption was positively associated with CVD [hazard ratio (HR) 1.11, 95% confidence interval (CI) 1.05 to 1.16 for unprocessed red meat (per 100 g/day increment); 1.26, 95% CI 1.18 to 1.35 for processed red meat (per 50 g/day increment)], CVD subtypes, T2DM, and GDM. The associations with stroke and T2DM were higher in western settings, with no difference by sex. CONCLUSION: Unprocessed and processed red meat consumption are both associated with higher risk of CVD, CVD subtypes, and diabetes, with a stronger association in western settings but no sex difference. Better understanding of the mechanisms is needed to facilitate improving cardiometabolic and planetary health."}