{"id":"da3343d4e35d","type":"article","url":"https://hartvaat.nl/2025/08/01/opnameduur-en-eerdere-hf-opnames-bij-frailteit-en-hartfalen-systematische-review/","title":"Opnameduur en eerdere HF-opnames bij frailteit en hartfalen: systematische review","title_en":"Length of stay and prior heart failure admission in frailty and heart failure: A systematic review and meta-analysis.","category":"hartfalen","category_label":"Hartfalen","professions":["cardioloog","huisarts"],"tags":["acuut-hartfalen"],"journal":"ESC heart failure","doi":"10.1002/ehf2.15300","source_url":"https://doi.org/10.1002/ehf2.15300","authors":["Konstantinos Prokopidis","Amy Nortcliffe","Chukwuma Okoye","Massimo Venturelli","Gregory Y H Lip","Masoud Isanejad"],"significance":5,"published":"2025-08-01","source_date":"2025-08-01","image":"","kennis":["https://hartvaat.nl/kennis/hartfalen/palliatief-hartfalen/"],"congress":"","summary_en":"A systematic review and meta-analysis documented the relationship between frailty, hospital length of stay, and prior heart failure admissions. Frail patients had significantly longer hospitalisations and more readmissions, underscoring the need for targeted transitional care.","created":"2026-07-03T10:31:45Z","updated":"2026-07-03T18:39:16Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Review documenteerde de relatie tussen verblijfsduur, eerdere HF-opnames en frailteit. Fragiele patiënten hebben langere opnames en meer heropnames, wat gerichte transitiezorg vereist.","abstract_original":"AIMS: The aim of this study was to compare the differences in length of stay (LoS) and prior hospitalization due to heart failure (HHF) in patients with HF and frailty versus without frailty. METHODS AND RESULTS: From inception until August 2024, PubMed, Scopus, Web of Science and Cochrane Library were searched. To examine the association related to LoS and HHF in patients with HF, a meta-analysis using a random-effects model was conducted (CRD42024570604). Our main analysis demonstrated a significantly increased LoS in patients with frailty versus those without frailty [n = 10; mean difference (MD): 3.67; 95% CI: 2.26-5.08, I2 = 93%, P < 0.01]. Likewise, patients with frailty had significantly increased odds of HHF [n = 17; odds ratio (OR): 1.76; 95% CI: 1.50-2.07, I2 = 81%, P < 0.01]. Risk of bias assessment of the included studies was overall fair, while Egger's test showed publication bias regarding studies that examined LoS (P = 0.02). CONCLUSIONS: Patients with frailty have longer LoS and more frequent HHF, underscoring the need for early, targeted interventions to manage frailty that may be attributed primarily to ageing and comorbidity-related status."}