{"id":"39c677e6bffa","type":"article","url":"https://hartvaat.nl/2025/12/18/gedeeltelijk-succesvolle-bijniervenesampling-bij-subtypering-van-primair-aldoste/","title":"Gedeeltelijk succesvolle bijniervenesampling bij subtypering van primair aldosteronisme","title_en":"Partially Successful Adrenal Vein Sampling With and Without Cross-Sectional Imaging in Primary Aldosteronism Subtyping","category":"hypertensie","category_label":"Hypertensie","professions":["cardioloog","internist"],"tags":["vrouwen"],"journal":"Hypertension","doi":"https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.125.26149","source_url":"https://doi.org/https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.125.26149","authors":["Peeradon Vibhatavata"],"significance":6,"published":"2025-12-18","source_date":"2025-12-18","image":"","kennis":[],"congress":"","summary_en":"This study addressed the clinical interpretation of partially successful adrenal vein sampling in primary aldosteronism, providing guidance when only one adrenal vein is successfully cannulated.","created":"2026-07-03T10:25:40Z","updated":"2026-07-03T13:25:03Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Bijniervenesampling (AVS) wordt gebruikt om therapie te sturen bij primair aldosteronisme. Wanneer slechts één bijniervene succesvol wordt gecatheteriseerd, kan de relatieve aldosteron-secretie-index worden gebruikt. Deze studie onderzocht de rol van beeldvorming.","abstract_original":"Hypertension, Volume 83, Issue 5, Page e26149, May 1, 2026. BACKGROUND:Adrenal vein (AV) sampling (AVS) is used to guide therapy in primary aldosteronism (PA). When a single AV is successfully cannulated, the relative aldosterone secretion index (RASI), which compares the aldosterone/cortisol ratio in that AV versus the periphery, has been proposed as sufficient for PA subtyping, particularly when <1. Data on RASI reliability have, however, been inconsistent.METHODS:This retrospective cohort study included patients with PA who underwent AVS before and after cosyntropin stimulation at a referral center between January 2015 and December 2024. To simulate partially successful AVS, RASI was calculated in patients with successful bilateral AV cannulation and compared across PA subtypes and postoperative outcomes, with assessment of distributional overlap.RESULTS:Of 460 patients (mean age 53±12 years; 58% men), bilateral AVS was successful in 437 patients at baseline and in all patien"}