{"id":"281ddb320d93","type":"article","url":"https://hartvaat.nl/2025/12/26/pth-suppressieprofielen-na-orale-calciumbelasting-bij-niertransplantatiepatiente/","title":"PTH-suppressieprofielen na orale calciumbelasting bij niertransplantatiepatiënten","title_en":"Parathyroid hormone suppression profiles following oral calcium challenge in kidney transplant recipients","category":"chronische nierziekte","category_label":"Nierziekte","professions":["internist"],"tags":["niertransplantatie"],"journal":"Kidney International","doi":"https://www.kidney-international.org/article/S0085-2538(25)01010-5/fulltext","source_url":"https://doi.org/https://www.kidney-international.org/article/S0085-2538(25)01010-5/fulltext","authors":["Jordan Desenclos","Caroline Halimi","Emmanuelle Vidal-Petiot","Justina Motiejunaite","Eric Daugas","Tiphaine Robert-Mercier","Anne Boutten","Marie-Noëlle Peraldi","Corinne Antoine","François Vrtovsnik","Christine Randoux","Guillaume Hanouna","Quentin Raimbourg","Martin Flamant","Nahid Tabibzadeh"],"significance":5,"published":"2025-12-26","source_date":"2025-12-26","image":"","kennis":["https://hartvaat.nl/kennis/nierziekte/nsaids-en-nierziekte/"],"congress":"","summary_en":"This study characterised parathyroid hormone suppression profiles after oral calcium challenge in kidney transplant recipients with post-transplant hyperparathyroidism. The calcium-mediated PTH suppression patterns were associated with PTH control in the first year post-transplant.","created":"2026-07-03T10:25:38Z","updated":"2026-07-03T13:25:02Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Post-transplantatie hyperparathyreoïdie is veelvoorkomend en geassocieerd met ongunstige uitkomsten. De bijdragen van calciumbiobeschikbaarheid en bijschildklierresponsiviteit zijn slecht gedefinieerd. Deze studie onderzocht het PTH-suppressieprofiel na orale calciumbelasting.","abstract_original":"Post-kidney transplant (KT) hyperparathyroidism (PT-HPT) is common and linked to adverse outcomes, yet the contributions of calcium bioavailability and parathyroid responsiveness remain poorly defined. Here, we studied the trajectory of oral calcium-mediated PTH suppression (CMPS) in PT-HPT and its association with PTH control in the first year post-KT."}