{"id":"3f829cc231b6","type":"article","url":"https://hartvaat.nl/2025/12/29/functionele-en-morfologische-karakterisering-van-coronaire-atherosclerose/","title":"Functionele en morfologische karakterisering van coronaire atherosclerose","title_en":"Functional and morphological characterization of coronary atherosclerosis","category":"cholesterol","category_label":"Cholesterol","professions":["cardioloog"],"tags":["atherosclerose"],"journal":"Atherosclerosis","doi":"https://www.atherosclerosis-journal.com/article/S0021-9150(25)01530-8/fulltext","source_url":"https://doi.org/https://www.atherosclerosis-journal.com/article/S0021-9150(25)01530-8/fulltext","authors":["Koshiro Sakai","Toshiro Shinke","Ziad Ali","Takuya Mizukami","Hitoshi Matsuo","Hirohiko Ando","Tetsuya Amano","Thomas Engstrøm","Jeroen Sonck","Adriaan Wilgenhof","Divaka Perera","Masafumi Nakayama","William F. Fearon","Brian Ko","Javier Escaned","Daniel Munhoz","Frederic Bouisset","Kazumasa Ikeda","Taito Arai","Ethan Korngold","Evald Høj Christiansen","Colin Berry","Bernard De Bruyne","Nils P. Johnson","Carlos Collet"],"significance":5,"published":"2025-12-29","source_date":"2025-12-29","image":"","kennis":[],"congress":"","summary_en":"This study provides functional and morphological characterisation of coronary atherosclerosis using the novel Pullback Pressure Gradient metric to classify disease into focal or diffuse patterns. The physiological assessment complements anatomical imaging for treatment planning.","created":"2026-07-03T10:25:38Z","updated":"2026-07-03T13:25:01Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"De interactie tussen coronaire hemodynamiek en atherosclerotische plaque is onvolledig begrepen. De Pullback Pressure Gradient (PPG) categoriseert coronaire ziekte in focale of diffuse patronen. Deze studie karakteriseert atherosclerose functioneel en morfologisch.","abstract_original":"The interplay between coronary artery hemodynamics and atherosclerotic plaque is not fully understood. The Pullback Pressure Gradient (PPG), a novel physiological metric, categorizes coronary artery disease (CAD) into focal or diffuse patterns based on coronary physiology."}