{"id":"3f75fd595ae0","type":"article","url":"https://hartvaat.nl/2026/01/05/klinisch-spectrum-van-parvovirus-b19-geassocieerde-acute-myocarditis-bij-kindere/","title":"Klinisch spectrum van parvovirus B19-geassocieerde acute myocarditis bij kinderen","title_en":"Clinical Spectrum of Children With Parvovirus B19–Associated Acute Myocarditis","category":"algemeen","category_label":"Algemeen","professions":["cardioloog","huisarts"],"tags":[],"journal":"Circulation","doi":"https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.125.075943","source_url":"https://doi.org/https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.125.075943","authors":["Enrico Ammirati"],"significance":7,"published":"2026-01-05","source_date":"2026-01-05","image":"","kennis":["https://hartvaat.nl/kennis/kleplijden/kleppathologie-reumatische-origine/","https://hartvaat.nl/kennis/cardiometabool/hart-en-kanker-cardio-oncologie/"],"congress":"","summary_en":"This Circulation study characterized the clinical spectrum of parvovirus B19-associated acute myocarditis in children, describing the presentation, diagnosis, and outcomes of this viral cardiac complication in the pediatric population.","created":"2026-07-03T10:25:36Z","updated":"2026-07-03T13:24:59Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Parvovirus B19 wordt overgedragen via druppelinfectie en veroorzaakt gewoonlijk erythema infectiosum, maar kan ook acute myocarditis veroorzaken. Na de Europese uitbraak in 2024 beschrijft deze studie het klinische spectrum bij kinderen.","abstract_original":"BACKGROUND:Parvovirus B19 is a DNA virus transmitted via respiratory droplets, commonly causing erythema infectiosum in children but also implicated in acute myocarditis. In 2024, an outbreak of parvovirus B19 infections was reported across Europe and the United States. Despite growing awareness, data on the clinical features and outcomes of children with parvovirus B19–associated acute myocarditis remain limited.METHODS:This multicenter retrospective observational study reviewed medical records of pediatric patients (<18 years of age) admitted with acute myocarditis to 11 Italian tertiary pediatric cardiac centers between January 1, 2022, and October 31, 2024. Of 217 cases, 66 had confirmed parvovirus B19 DNA in plasma (PVB19+), whereas 82 with negative parvovirus B19 testing served as a comparator group (PVB19−). Population-based incidence trends of pediatric myocarditis were also evaluated in the Lombardy region from 2004 through 2024.RESULTS:Among PVB19+acute myocarditis cas"}