# GoFresh: DASH-boodschappen en bloeddrukeffect — RCT

*geplaatst 2026-01-06 · Cholesterol · JAMA · doi 10.1001/jama.2025.21112 · https://hartvaat.nl/2026/01/06/gofresh-dash-boodschappen-en-bloeddrukeffect-rct/*

De GoFresh-trial onderzocht of bezorging van DASH-dieetboodschappen de bloeddruk verlaagt. De interventie verbeterde de voedselkeuze en verlaagde de bloeddruk bescheiden.

## English: DASH-Patterned Groceries and Effects on Blood Pressure: The GoFresh Randomized Clinical Trial.

The GoFresh randomized trial showed that home delivery of DASH-patterned groceries improves dietary quality and lowers blood pressure in Black adults, demonstrating that removing food access barriers translates to measurable health benefit.

## Abstract (original, from the publication)

IMPORTANCE: The Dietary Approaches to Stop Hypertension (DASH) eating plan lowered blood pressure (BP) among Black adults in a controlled environment, but to date, there are no grocery shopping strategies that replicated its health effects in a community setting. OBJECTIVE: The Groceries for Black Residents of Boston to Stop Hypertension (GoFresh) trial was conducted to determine the effects of low sodium-DASH groceries on systolic BP. DESIGN, SETTING, AND PARTICIPANTS: This parallel-group randomized clinical trial was conducted in Boston from August 2022 to September 2025 among Black residents of urban communities with few grocery stores, a systolic BP of 120 to less than 150 mm Hg, a diastolic BP less than 100 mm Hg, and no hypertension treatment. Data were analyzed from June through October 2025. INTERVENTIONS: Participants were randomly assigned to 12 weeks of home-delivered, DASH-patterned groceries ordered weekly with dietitian counseling without emphasizing cost or three $500 stipends every 4 weeks intended for self-directed grocery shopping. MAIN OUTCOMES AND MEASURES: The primary comparison was the difference in the 3-month change in model-estimated office systolic BP (based on 3 measurements over at least 2 visits) between interventions. Adherence was assessed via 24-hour urine collection. Secondary outcomes included diastolic BP, body mass index (BMI), hemoglobin A1c levels, and low-density lipoprotein (LDL) cholesterol. Maintenance of effects was assessed 3 months after intervention cessation. RESULTS: Among 180 participants, (mean [SD] age, 46.1 [13.3] years; 102 female [56.7%]; 180 self-reported Black [100%]; 12 Hispanic [6.7%]), 175 individuals (97.2%) completed the primary outcome assessment. Mean (SD) baseline systolic BP and diastolic BP were 130.0 (6.7) mm Hg and 79.8 (8.1) mm Hg. At 3 months, the mean systolic BP changed -5.7 mm Hg (95% CI, -7.4, to-3.9 mm Hg) in the DASH-patterned group and -2.3 mm Hg (95% CI, -4.1 to -0.4 mm Hg) in the self-directed group (difference in changes, -3.4 mm Hg; 95% CI, -5.9 to -0.8 mm Hg; P = .009). Compared with the self-directed group, after 3 months the DASH-patterned group changed mean diastolic BP by -2.4 mm Hg (95% CI, -4.2 to -0.5 mm Hg), urine sodium level by -545 mg/24 h (95% CI, -1041 to -50 mg/24 h), and LDL cholesterol by -8.0 mg/dL (95% CI, -13.7 to -2.3 mg/dL) (to convert LDL cholesterol to millimoles per liter, multiply by 0.0259). Effects were not maintained 6 months after the intervention was initiated. No effects occurred in BMI or hemoglobin A1c level. CONCLUSIONS AND RELEVANCE: In this study, a program of home-delivered, DASH-style groceries plus dietitian counseling decreased BP and LDL cholesterol levels beyond comparable monetary compensation. However, effects were not maintained after the intervention ended. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT05121337.

Auteurs: Stephen P Juraschek, Hannah Col, Kayla Ferro, Ruth-Alma N Turkson-Ocran, Jennifer L Cluett, Roger B Davis, Kristen M Kraemer, Kathy McManus, Kenneth J Mukamal, Emily L Aidoo, Fredrick Larbi Kwapong, Marian Budu, Dhrumil Patil, Sarah Nartey, Jacqueline Michetti, Sofia Allison, Manfred Mate-Kole, Jingyi Cao, Benjamin Grobman, Reva Seager, Anika L Hines, Edgar R Miller, Deidra C Crews, Stephanie L Fitzpatrick

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Bron: JAMA, https://doi.org/10.1001/jama.2025.21112. Bijgewerkt 2026-07-03T13:31:04Z. Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.