{"id":"e5e61f6383e0","type":"article","url":"https://hartvaat.nl/2026/01/13/risicofactoren-en-plaquevolume-op-coronaire-ct-angiografie-lessen-uit-het-advanc/","title":"Risicofactoren en plaquevolume op coronaire CT-angiografie: lessen uit het ADVANCE-register","title_en":"The association of risk factors on coronary computed tomography angiography derived atherosclerotic plaque volume - Lessons from the ADVANCE registry","category":"cholesterol","category_label":"Cholesterol","professions":["cardioloog"],"tags":["biomarkers-cardiovasculair","coronaire-ct-angiografie"],"journal":"Atherosclerosis","doi":"https://www.atherosclerosis-journal.com/article/S0021-9150(25)01413-3/fulltext","source_url":"https://doi.org/https://www.atherosclerosis-journal.com/article/S0021-9150(25)01413-3/fulltext","authors":["Alexander Haenel","Ruurt A. Jukema","John K. Khoo","Fionn Coughlan","Philipp Blanke","Aaisha Ferkh","Timothy Fairbairn","Nicholas Ng","Lynne M. Koweek","Pamela Douglas","Mark Rabbat","Gianluca Pontone","Kavitha M. Chinnaiyan","Bernard De Bruyne","Jeroen Bax","Tetsuya Amano","Koen Nieman","Campbell Rogers","Hironori Kitabata","Niels PR. Sand","Tomohiro Kawasaki","Sarah Mullen","Whitney Huey","Hitoshi Matsuo","Manesh Patel","Bjarne L. Nørgaard","Jonathon A. Leipsic","Georgios Tzimas","The ADVANCE investigators"],"significance":5,"published":"2026-01-13","source_date":"2026-01-13","image":"","kennis":["https://hartvaat.nl/kennis/preventie/levenslang-cardiovasculair-risico/","https://hartvaat.nl/kennis/lipiden/lp-a-verhoogd/"],"congress":"","summary_en":"Cross-sectional analysis of the ADVANCE registry using AI-based quantitative plaque assessment found that cardiovascular risk factors are only modestly associated with total coronary plaque volume on CT angiography. The findings suggest additional determinants of plaque burden beyond traditional risk factors.","created":"2026-07-03T10:25:33Z","updated":"2026-07-03T13:24:57Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Cross-sectionele analyse van het ADVANCE-register met AI-gebaseerde kwantitatieve plaquebeoordeling toont dat cardiovasculaire risicofactoren slechts matig geassocieerd zijn met het totale plaquevolume op coronaire CT-angiografie.","abstract_original":"Cross-sectional analysis of the ADVANCE registry using artificial intelligence-based quantitative plaque assessment showed that cardiovascular risk factors are only modestly associated with total plaque volume on CCTA."}