{"id":"002c33b6a02b","type":"article","url":"https://hartvaat.nl/2026/01/20/het-onbekende-uit-ckdu-halen-optimale-benaderingen-voor-epidemische-nierziekte/","title":"Het 'onbekende' uit CKDu halen: optimale benaderingen voor epidemische nierziekte","title_en":"Taking the “unknown” out of CKDu—optimizing approaches to uncover the cause(s) of epidemic-level kidney disease in low- and middle-income settings: a report from the ISN’s International Consortium of CKDu Collaborators (ISN i3C)","category":"chronische nierziekte","category_label":"Nierziekte","professions":["internist"],"tags":[],"journal":"Kidney International","doi":"https://www.kidney-international.org/article/S0085-2538(26)00011-6/fulltext","source_url":"https://doi.org/https://www.kidney-international.org/article/S0085-2538(26)00011-6/fulltext","authors":["Ben Caplin","Shuchi Anand","Marvin González-Quiroz","Magdalena Madero","Marie Michael","Sumit Mohan","Anna Strasma","Sundararaman Swaminathan","Sushrut Waikar","Eranga Wijewickrama","ISN i3C Working Group"],"significance":5,"published":"2026-01-20","source_date":"2026-01-20","image":"","kennis":[],"congress":"","summary_en":"An ISN i3C report discusses optimised approaches to uncover the causes of chronic kidney disease of undetermined aetiology, which remains a major mortality cause in low- and middle-income settings despite two decades of research.","created":"2026-07-03T10:25:32Z","updated":"2026-07-03T13:24:56Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"CKD van onbekende etiologie (CKDu) is een belangrijke doodsoorzaak in lage- en middeninkomensregionen. Ondanks twee decennia onderzoek blijven de oorzaken onduidelijk. Dit ISN i3C-rapport bespreekt geoptimaliseerde benaderingen om de oorzaken te achterhalen.","abstract_original":"Chronic kidney disease of undetermined etiology (CKDu) is a major cause of mortality that affects communities, health systems, and national economies. Despite 2 decades of descriptive and analytical research, the causes of CKDu epidemics remain unclear. In February 2025, at the World Congress of Nephrology, the International Society of Nephrology’s International Consortium of CKDu Collaborators met to discuss the obstacles to determining the cause(s) of the epidemics. Several key themes were identified: First, differences in CKDu burden between regions are poorly described, and this is complicated by inconsistent terminology."}