{"id":"75820b987c66","type":"article","url":"https://hartvaat.nl/2026/02/04/determinanten-van-placentaire-versus-maternale-pre-eclampsie/","title":"Determinanten van placentaire versus maternale pre-eclampsie","title_en":"Determinants of Placental Versus Maternal Preeclampsia","category":"hypertensie","category_label":"Hypertensie","professions":["huisarts","internist"],"tags":["zwangerschap-hart"],"journal":"Hypertension","doi":"https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.125.26236","source_url":"https://doi.org/https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.125.26236","authors":["Omonigho Aisagbonhi"],"significance":5,"published":"2026-02-04","source_date":"2026-02-04","image":"","kennis":[],"congress":"","summary_en":"This study evaluated clinical classification systems for distinguishing placental from maternal preeclampsia based on placental pathological features. The findings inform subtype-specific approaches to preeclampsia management and prevention.","created":"2026-07-03T10:25:26Z","updated":"2026-07-03T13:24:51Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"De placenta is cruciaal bij het ontstaan van pre-eclampsie, maar bij sommige gevallen ontbreekt identificeerbare placentapathologie. Deze studie evalueerde welk klinisch classificatiesysteem het best onderscheidt tussen placentaire en maternale pre-eclampsie.","abstract_original":"Hypertension, Volume 83, Issue 4, Page e26236, April 1, 2026. BACKGROUND:The placenta is known to be critical in the etiology of preeclampsia. However, there is a subset of preeclampsia cases without identifiable placental pathology. We evaluated which clinical preeclampsia classification system best distinguishes preeclampsia with placental pathology from preeclampsia without placental pathology.METHODS:We evaluated 5 placental pathological features in 197 placentas from patients with preeclampsia grouped by 3 clinical preeclampsia subclasses: (1) preeclampsia with calculated infant birthweight <10th percentile for gestational age (small for gestational age [SGA] preeclampsia) versus preeclampsia with birthweight ≥10th percentile for gestational age (not SGA preeclampsia); (2) preeclampsia with delivery before 34 weeks of gestation (early delivery preeclampsia) versus preeclampsia with delivery at or after 34 weeks of gestation (late delivery preeclampsia); and (3) preeclampsia"}