# Postprandiale hypotensie en valrisico bij oudere hypertensieve patiënten (AMBROSIA)

*geplaatst 2026-02-05 · Hypertensie · Hypertension · doi https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.125.25518 · https://hartvaat.nl/2026/02/05/postprandiale-hypotensie-en-valrisico-bij-oudere-hypertensieve-patienten-ambrosi/*

Postprandiale hypotensie kan bijdragen aan vallen bij ouderen die antihypertensiva gebruiken. In de AMBROSIA-studie werd met ambulante bloeddrukmonitoring het verband onderzocht tussen postprandiale hypotensie en valincidenten bij thuiswonende ouderen.

## English: Association Between Postprandial Hypotension Determined by Ambulatory Blood Pressure Monitoring and Falls Among Older Adults With Hypertension Who Are Taking Antihypertensive Medication: Results From the AMBROSIA Study

This AMBROSIA study showed that postprandial hypotension detected by ambulatory monitoring is associated with falls in older adults taking antihypertensive medication, identifying a modifiable risk factor for fall prevention.

## Abstract (original, from the publication)

Hypertension, Volume 83, Issue 4, Page e25518, April 1, 2026. BACKGROUND:Postprandial hypotension (PPH) may contribute to falls among older adults, particularly those taking antihypertensive medication. However, evidence on this association in community-dwelling populations is limited. Since ambulatory blood pressure (BP) monitoring captures BP during daily activities, it may provide accurate assessments of PPH outside the clinic setting.METHODS:This prospective cohort study examined the association between PPH and fall risk among community-dwelling adults aged ≥65 years taking antihypertensive medication. At baseline, participants underwent 24-hour ambulatory BP monitoring; subsequently, they completed monthly fall calendars during a 12-month follow-up. PPH by systolic BP (SBP; systolic PPH) was defined as a postprandial SBP decline, mean SBP during the hour before the meal minus the minimum SBP during the 2 hours after the meal, following any meal of ≥20 mm Hg, or a decrease to SBP ≤

Auteurs: Keisuke Narita

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Bron: Hypertension, https://doi.org/https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.125.25518. Bijgewerkt 2026-07-03T18:38:15Z. Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.