{"id":"7260f88c15c9","type":"article","url":"https://hartvaat.nl/2026/02/19/enkelvoudige-onverzadigde-vetzuren-in-vetweefsel-en-het-risico-op-perifeer-vaatl/","title":"Enkelvoudige onverzadigde vetzuren in vetweefsel en het risico op perifeer vaatlijden","title_en":"Monounsaturated Fatty Acids in Adipose Tissue and the Risk of Peripheral Artery Disease: A Danish Case-Cohort study","category":"cholesterol","category_label":"Cholesterol","professions":["huisarts","internist"],"tags":[],"journal":"Atherosclerosis","doi":"https://www.atherosclerosis-journal.com/article/S0021-9150(26)00051-1/fulltext","source_url":"https://doi.org/https://www.atherosclerosis-journal.com/article/S0021-9150(26)00051-1/fulltext","authors":["Jonas Pedersen","Alberte Sjælland","Frederik Kistrup Gerth Kramme","Jytte Halkjær","Anja Olsen","Christina C. Dahm","Kirsten B. Holven","Erik Berg Schmidt","Stine Krogh Venø","Christian Bork"],"significance":5,"published":"2026-02-19","source_date":"2026-02-19","image":"","kennis":[],"congress":"","summary_en":"A Danish case-cohort study examined the association between individual monounsaturated fatty acids in adipose tissue and the risk of peripheral artery disease. The findings nuance dietary recommendations on replacing saturated fats with MUFAs.","created":"2026-07-03T10:24:55Z","updated":"2026-07-03T13:24:24Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"In een Deens case-cohortonderzoek werd de samenstelling van enkelvoudig onverzadigde vetzuren (MUFA) in vetweefsel onderzocht in relatie tot het risico op perifeer arterieel vaatlijden. De bevindingen nuanceren het advies om verzadigde vetten te vervangen door MUFA's.","abstract_original":"Dietary guidelines recommend replacing saturated fatty acids with poly- or monounsaturated fatty acids (MUFA) to lower the risk of cardiovascular disease. The biological effects of MUFAs may differ between individual MUFAs, while their role in development of peripheral artery disease (PAD) remains unknown. We investigated associations between the content of MUFAs in adipose tissue and the risk of incident PAD."}