{"id":"f202fadafac3","type":"article","url":"https://hartvaat.nl/2026/02/19/evolocumab-en-doorgankelijkheid-van-veneuze-bypasses-na-cabg-newton-cabg-cardiol/","title":"Evolocumab en doorgankelijkheid van veneuze bypasses na CABG: NEWTON-CABG CardioLink-5","title_en":"Evaluation of evolocumab on saphenous vein graft patency following coronary artery bypass graft surgery in people living with and without diabetes in the NEWTON-CABG CardioLink-5 trial.","category":"cholesterol","category_label":"Cholesterol","professions":["apotheker","cardioloog"],"tags":["coronaire-bypass","evolocumab","newton-cabg","pcsk9-remmers-nieuwe-generatie"],"journal":"Diabetes, obesity & metabolism","doi":"10.1111/dom.70590","source_url":"https://doi.org/10.1111/dom.70590","authors":["Hwee Teoh","Subodh Verma","G B John Mancini","Adrian Quan","Michael Szarek","Randi Elituv","Meena Verma","Elizabeth Misner","Aishwarya Krishnaraj","Peter Jüni","Michael J Koren","Stephen J Nicholls","Deepak L Bhatt","C David Mazer","Lawrence A Leiter"],"significance":5,"published":"2026-02-19","source_date":"2026-02-19","image":"","kennis":["https://hartvaat.nl/kennis/lipiden/lpa-meten-wanneer-waarom/","https://hartvaat.nl/kennis/preventie/statines-primaire-preventie/"],"congress":"","summary_en":"The NEWTON-CABG CardioLink-5 trial evaluated whether adding evolocumab to statin therapy improves saphenous vein graft patency after coronary artery bypass surgery, with separate analysis for patients with and without diabetes.","created":"2026-07-03T10:24:57Z","updated":"2026-07-03T13:24:26Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"De NEWTON-CABG CardioLink-5-trial onderzocht of toevoeging van evolocumab (PCSK9-remmer) aan statinetherapie de doorgankelijkheid van veneuze bypasses na coronaire bypasschirurgie verbetert, met aparte analyse voor patiënten met en zonder diabetes.","abstract_original":""}