{"id":"0af91094fab6","type":"article","url":"https://hartvaat.nl/2026/03/01/slappe-verlamming-en-tetanie-na-chemotherapie-een-diagnostische-uitdaging/","title":"Slappe verlamming en tetanie na chemotherapie: een diagnostische uitdaging","title_en":"The Case | Flaccid paralysis and tetany after chemotherapy: a diagnostic challenge","category":"chronische nierziekte","category_label":"Nierziekte","professions":["internist"],"tags":[],"journal":"Kidney International","doi":"https://www.kidney-international.org/article/S0085-2538(25)00742-2/fulltext","source_url":"https://doi.org/https://www.kidney-international.org/article/S0085-2538(25)00742-2/fulltext","authors":["Carolin Herzog","Peter R. Mertens","Florian G. Scurt"],"significance":4,"published":"2026-03-01","source_date":"2026-03-01","image":"","kennis":[],"congress":"","summary_en":"A diagnostic challenge case of a 75-year-old woman with cervical carcinoma who developed flaccid paralysis and tetany after chemotherapy, illustrating complex electrolyte disturbances requiring systematic evaluation.","created":"2026-07-03T10:25:15Z","updated":"2026-07-03T13:24:41Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Een 75-jarige vrouw met cervixcarcinoom werd opgenomen wegens snelle achteruitgang na chemotherapie. Zonder voorgeschiedenis van nierziekte ontwikkelde zij slappe verlamming en tetanie, wat een complexe diagnostische puzzel opleverde.","abstract_original":"A 75-year-old woman with cervical carcinoma that had spread through the lymph nodes and to other nearby tissues was admitted for emergency evaluation because of a rapid deterioration in her condition. She had no history of kidney disease, with a baseline creatinine of 70.4 μmol/l (0.8 mg/dl) and an estimated glomerular filtration rate >60 ml/min per 1.73 m2. Her presentation occurred 4 days after she had received her fifth cycle of cisplatin chemotherapy, administered at a dose of 40 mg/m2 per cycle for a cumulative dose of 200 mg/m2."}