# Aorta- en iliacale calcificaties voorspellen dissectie, aneurysmaruptuur en perifeer vaatlijden

*geplaatst 2026-03-19 · Algemeen · Circulation · doi https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.125.076240 · https://hartvaat.nl/2026/03/02/aorta-en-iliacale-calcificaties-voorspellen-dissectie-aneurysmaruptuur-en-perife/*

Deze prospectieve cohortstudie uit de DANCAVAS-trials onderzocht of aorta- en iliacale calcificaties op CT aortadissectie, aneurysmaruptuur en perifeer vaatlijden voorspellen. De populatiegebaseerde data tonen dat calcificatiescores een bruikbare risicostratificatie bieden voor deze ernstige vasculaire events.

## English: Aortic and Iliac Calcifications as Predictors of Aortic Dissection, Aneurysm Rupture, and Peripheral Vascular Disease: A Prospective Cohort Study from the DANCAVAS Trials

This prospective cohort study showed that aortic and iliac calcifications on CT predict aortic dissection, aneurysm rupture, and peripheral vascular events, establishing vascular calcification as a marker for acute aortic complications.

## Abstract (original, from the publication)

BACKGROUND:There is limited evidence of the relationship between aortic and iliac calcification and aortic events (aortic dissection or aneurysm rupture) and major adverse limb events (MALEs; peripheral revascularization and lower limb amputation). The aim of this population-based prospective cohort study was to investigate the association of aortic and iliac calcifications with aortic events and MALEs.METHODS:All participants from the DANCAVAS (Danish Cardiovascular Screening) trials who received a full thoracoabdominal aortic computed tomography scan with recorded measurements of aortic and iliac calcification were included. The aorta and iliac artery calcifications were measured in a 5-segment model and categorized into quartiles, apart from the ascending aorta, which was categorized into 4 exposure groups, as the majority of participants had no calcification in the ascending aorta. The participants were followed from inclusion in the DANCAVAS trial until aortic events, MALE, death,

Auteurs: Cecilie Skov Petersen

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Bron: Circulation, https://doi.org/https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.125.076240. Bijgewerkt 2026-07-03T13:31:32Z. Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.