{"id":"bc11ee06d4d9","type":"article","url":"https://hartvaat.nl/2026/03/02/pam-vt-2-littekenverloop-na-vt-ablatie-beoordeeld-met-seriele-cardiale-mri/","title":"PAM-VT 2: littekenverloop na VT-ablatie beoordeeld met seriële cardiale MRI","title_en":"","category":"algemeen","category_label":"Algemeen","professions":["cardioloog"],"tags":[],"journal":"Circulation","doi":"https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.125.074748","source_url":"https://doi.org/https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.125.074748","authors":["Ivo Roca"],"significance":6,"published":"2026-03-25","source_date":"2026-03-02","image":"","kennis":["https://hartvaat.nl/kennis/diagnostiek/cardiale-mri/"],"congress":"","summary_en":"The PAM-VT 2 study used serial late gadolinium enhancement cardiac MRI to assess the long-term evolution of scar and ablation lesions after ventricular tachycardia ablation. The prospective study provides insight into how substrate and ablation lesions change over time, relevant for predicting recurrences.","created":"2026-07-03T10:32:38Z","updated":"2026-07-03T13:31:34Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"De PAM-VT 2-studie gebruikte seriële late gadolinium enhancement cardiale MRI om de langetermijnevolutie van littekens en ablatielaesies na VT-ablatie te beoordelen. De prospectieve studie biedt inzicht in hoe substraat en ablatieletsels veranderen over de tijd, wat relevant is voor het voorspellen van recidieven.","abstract_original":"BACKGROUND:Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) is useful for identifying ventricular tachycardia (VT) substrate in patients with structural heart disease. While preprocedural LGE-CMR is widely used for planning, the role of postprocedural LGE-CMR in evaluating VT ablation success and long-term scar evolution has been less explored. This study aimed to prospectively and systematically assess the long-term evolution of scar and ablation lesions using serial postablation LGE-CMR with long-term follow-up.METHODS:This prospective study included 51 patients (mean age, 65.2±9.8 years; men, 95.8%; ischemic heart disease, 83%; left ventricular ejection fraction, 34.5±10.4%) undergoing their first substrate-based VT ablation between March 2019 and July 2020. Preprocedural LGE-CMR and 2 postprocedural scans at 3 to 6 months (CMR-1) and 18 to 24 months (CMR-2) were performed. Scar characteristics, including core scar, border zone, and conducting channels, were analyzed"}