{"id":"7f8989173c20","type":"article","url":"https://hartvaat.nl/2026/04/12/ehra-statement-pulsed-field-ablatie-als-nieuwe-standaard-voor-ablatie-bij-atrium/","title":"EHRA-statement: pulsed field-ablatie als nieuwe standaard voor ablatie bij atriumfibrilleren","title_en":"Pulsed Field Ablation for the Interventional Treatment of Atrial Fibrillation. A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), the Latin American Heart Rhythm Society (LAHRS) and the Canadian Heart Rhythm Society (CHRS).","category":"atriumfibrilleren","category_label":"Atriumfibrilleren","professions":["cardioloog"],"tags":["acuut-hartfalen","advent-trial","pulsed-field-ablatie","pulsed-field-ablatie-atriumfibrilleren"],"journal":"Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology","doi":"10.1093/europace/euag080","source_url":"https://doi.org/10.1093/europace/euag080","authors":["Michael Kühne","Patrick Badertscher","Jason G Andrade","Ante Anic","Julian Chun","Antonio Dello Russo","Pierre Jais","Josef Kautzner","Heiko Lehrmann","Claire Martin","Jose Merino","Damijan Miklavcic","Andrea Natale","Kars Neven","Armando Perez-Silva","Jonathan Piccini","Tobias Reichlin","Raphael Rosso","Martin Ruwald","Andrea Sarkozy","Daniel Scherr","Arian Sultan","Hiroshi Tada","Stylianos Tzeis","Atul Verma","Bradley Wilsmore","Helmut Pürerfellner"],"significance":9,"published":"2026-05-27","source_date":"2026-04-12","image":"","kennis":["https://hartvaat.nl/kennis/atriumfibrilleren/elektrisch-remodellering-atrium/","https://hartvaat.nl/kennis/atriumfibrilleren/katheterablatie-af/"],"congress":"","summary_en":"International scientific statement from EHRA, HRS, APHRS, LAHRS and CHRS on pulsed field ablation (PFA) for atrial fibrillation. Through irreversible electroporation, PFA achieves myocardial ablation while preserving surrounding structures such as nerves, vasculature and the esophagus. Randomized trials demonstrate efficacy comparable to radiofrequency and cryoballoon ablation, with clear advantages in safety and procedural efficiency. The statement summarizes biophysics, technology and clinical evidence and provides practical guidance for clinical implementation and operator training.","created":"2026-07-03T10:32:56Z","updated":"2026-07-03T18:39:33Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Internationale wetenschappelijke verklaring van EHRA, HRS, APHRS, LAHRS en CHRS over pulsed field-ablatie (PFA) bij atriumfibrilleren. Door irreversibele elektroporatie veroorzaakt PFA myocardablatie zonder schade aan omliggende structuren als zenuwen, bloedvaten en slokdarm. Gerandomiseerde studies tonen een werkzaamheid vergelijkbaar met radiofrequentie- en cryoballonablatie, met duidelijke voordelen op het gebied van veiligheid en procedureduur. De verklaring vat de biofysica, technologie en klinische evidentie samen en biedt praktische handvatten voor implementatie en operator-training.","abstract_original":"Pulsed field ablation has emerged as a novel non-thermal treatment modality with a distinct safety profile for the interventional treatment of atrial fibrillation. By inducing irreversible electroporation, pulsed field ablation achieves myocardial ablation while preserving surrounding structures such as nerves, vasculature, and the esophagus. This European Heart Rhythm Association (EHRA) of the European Society of Cardiology (ESC) scientific statement, endorsed by major international societies, reviews the biophysics, technology, clinical evidence, workflow, safety, and training aspects of pulsed field ablation. Randomized trials demonstrate comparable efficacy to radiofrequency and cryoballoon ablation, with advantages in safety and efficiency. The statement provides practical advice for clinical implementation, operator training, and identifies key gaps in evidence and priorities for future research and innovation."}