{"id":"7da9721e277e","type":"article","url":"https://hartvaat.nl/2026/05/04/microbioom-vriendelijk-dieet-di-gm-geassocieerd-met-27-minder-hartfalen-bij-pred/","title":"Microbioom-vriendelijk dieet (DI-GM) geassocieerd met 27% minder hartfalen bij prediabetes (NHANES n=15.219)","title_en":"","category":"hartfalen","category_label":"Hartfalen","professions":["cardioloog","huisarts","internist"],"tags":["diabetes-en-hart","diabetes-type-1","microbioom","vrouwen"],"journal":"ESC heart failure","doi":"10.1093/eschf/xvag125","source_url":"https://doi.org/10.1093/eschf/xvag125","authors":["Yuqing Huang","Yuling Yang","Jia Feng","Qiming Gong","Yueli Pu","Xia Fang","Yong Xu"],"significance":6,"published":"2026-06-30","source_date":"2026-05-04","image":"","kennis":[],"congress":"","summary_en":"Cross-sectional analysis of NHANES 2007-2018 data in 15,219 US adults with diabetes or prediabetes. The Dietary Index for Gut Microbiota (DI-GM) was calculated from two 24-hour dietary recalls covering 14 food groups linked to gut microbiota. Higher DI-GM scores were independently associated with lower heart failure risk (aOR 0.93 per point; 95% CI 0.89-0.98; p=0.005). Compared with scores 0-3, DI-GM ≥6 was associated with 27% lower HF risk (OR 0.73; 95% CI 0.58-0.92; p=0.007). The inverse association was stronger in prediabetes (OR 0.89 per point; p=0.004) but not significant in diabetes. Microbiota-related dietary patterns may thus play a role in HF prevention in metabolically vulnerable populations.","created":"2026-07-03T10:33:08Z","updated":"2026-07-03T13:32:03Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Cross-sectionele analyse van NHANES-data 2007-2018 bij 15.219 Amerikaanse volwassenen met diabetes of prediabetes. De Dietary Index for Gut Microbiota (DI-GM) werd berekend uit twee 24-uurs voedingsrecalls over 14 voedselgroepen die zijn gelinkt aan darmmicrobioom. Hogere DI-GM-scores waren onafhankelijk geassocieerd met lager hartfalen-risico (aOR 0,93 per punt; 95%-BI 0,89-0,98; p=0,005). Vergeleken met scores 0-3 was DI-GM ≥6 geassocieerd met 27% minder hartfalen (OR 0,73; 95%-BI 0,58-0,92; p=0,007). Het inverse verband was sterker bij prediabetes (OR 0,89 per punt; p=0,004) maar niet significant bij diabetes. Microbioom-gerelateerde voedingspatronen kunnen dus een rol spelen in HF-preventie bij metabool-kwetsbare populaties.","abstract_original":"AIMS: Diabetes and prediabetes markedly increase the risk of heart failure (HF), but the role of diet-gut microbiota interactions remains unclear. This study examined the association between the Dietary Index for Gut Microbiota (DI-GM) and HF risk among individuals with diabetes or prediabetes. METHODS: Data were obtained from 15 219 adults with diabetes or prediabetes in the US National Health and Nutrition Examination Survey (NHANES) 2007-2018. DI-GM scores were calculated from two 24-h dietary recalls covering 14 food groups linked to gut microbiota. Associations between DI-GM and prevalent HF were estimated using weighted logistic regression and restricted cubic spline models, adjusting for demographic, lifestyle, and metabolic factors. RESULTS: Participants had a mean age of 59.7 ± 13.2 years, and 48.3% were women. Higher DI-GM scores were independently associated with lower HF risk (adjusted odds ratio [OR] per 1-point increase = 0.93, 95% confidence interval [CI] 0.89-0.98; p = 0.005). Compared with scores 0-3, DI-GM ≥ 6 was linked to 27% lower HF risk (OR = 0.73, 95% CI 0.58-0.92; p = 0.007). The inverse association was stronger in prediabetes (OR = 0.89, 95% CI 0.82-0.96; p = 0.004) but not significant in diabetes. CONCLUSIONS: Higher DI-GM was associated with lower HF risk, particularly in prediabetes. Microbiota-related dietary patterns may play a role in HF prevention among metabolically at-risk populations."}