{"id":"09ac8ef4bbb6","type":"article","url":"https://hartvaat.nl/2026/05/25/kdigo-overzicht-de-nier-centraal-in-het-cardiovasculair-renaal-metabool-ckm-synd/","title":"KDIGO-overzicht: de nier centraal in het cardiovasculair-renaal-metabool (CKM) syndroom","title_en":"","category":"chronische nierziekte","category_label":"Nierziekte","professions":["cardioloog","huisarts","internist"],"tags":["anemie-ckd","bloeddrukbehandeling","bradycardie","cardio-renaal-metabool","cardiorenal-behandelstrategie","chronische-nierziekte","dapagliflozine","fidelio-dkd","figaro-dkd","niet-statine-therapie","obesitas","rosuvastatine"],"journal":"Kidney international","doi":"10.1016/j.kint.2026.03.031","source_url":"https://doi.org/10.1016/j.kint.2026.03.031","authors":["Adeera Levin","Nisha Bansal","Ian H de Boer","Morgan E Grams","Michel Jadoul","Jozine M Ter Maaten","Reem A Mustafa","Peter Rossing","Michael Cheung","Jennifer King","Amy Earley","Paul E Stevens"],"significance":8,"published":"2026-05-31","source_date":"2026-05-25","image":"","kennis":["https://hartvaat.nl/kennis/cardiometabool/diabetes-en-cardiovasculair-risico/","https://hartvaat.nl/kennis/cardiometabool/obesitas-en-hart/"],"congress":"","summary_en":"Review of KDIGO guidelines addressing the cardiovascular-kidney-metabolic (CKM) syndrome — formally recognised by the American Heart Association in 2023 as the integrated entity linking chronic kidney disease with obesity, diabetes, hypertension, dyslipidaemia, and cardiovascular disease. The review synthesises relevant KDIGO Clinical Practice Guidelines (CKD, blood pressure, diabetes, lipids), the upcoming guideline on heart failure in CKD, and Controversies Conference reports on obesity and CKD prevention. Core themes: early detection and intervention, personalised management of kidney and cardiovascular risk, and multidisciplinary care. KDIGO provides a robust framework for clinical practice and research priorities in patients at risk for or with CKM syndrome.","created":"2026-07-03T10:32:58Z","updated":"2026-07-03T13:31:53Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Overzichtsartikel over de KDIGO-richtlijnen voor het in 2023 door de American Heart Association erkende cardiovasculair-renaal-metabool (CKM) syndroom — de innige verwevenheid van chronische nierziekte met obesitas, diabetes, hypertensie, dyslipidemie en cardiovasculaire ziekte. De review bundelt de relevante KDIGO Clinical Practice Guidelines (CKD, bloeddruk, diabetes, lipiden), de aankomende richtlijn over hartfalen bij CKD en Controversies Conference-rapporten over obesitas en CKD-preventie. Centrale thema's: vroege detectie en interventie, persoonsgerichte beheersing van renaal en cardiovasculair risico, en multidisciplinaire zorg. Het KDIGO-kader biedt een robuust uitgangspunt voor de praktijk en richtinggevende onderzoeksprioriteiten bij personen met (risico op) CKM-syndroom.","abstract_original":"Chronic kidney disease (CKD) is closely intertwined with obesity, diabetes, hypertension, dyslipidemia, and cardiovascular disease (CVD). In 2023, the American Heart Association formally recognized these interconnections as a unified entity, the cardiovascular-kidney-metabolic (CKM) syndrome. The CKM syndrome brings renewed attention to the importance of CKD in CVD and reinforces the need for effective, evidence-based, interdisciplinary approaches to diagnose and prevent its intersecting components. The Kidney Disease: Improving Global Outcomes (KDIGO) organization has long led efforts to synthesize knowledge and translate evidence to practice in this area through the lens of the kidney. This review highlights KDIGO Clinical Practice Guidelines and Controversies Conference publications that directly address the CKM syndrome. These include guidelines addressing CKD, blood pressure, diabetes, and lipids; an upcoming guideline addressing heart failure in CKD; and Controversies Conference reports addressing obesity and CKD prevention. Overarching themes include the importance of early detection and intervention; comprehensive, personalized management of kidney and cardiovascular risk; and multidisciplinary care. Through integrated, evidence-based, disease-specific guidelines and reports, KDIGO has established a robust framework for the management of people at risk for or with CKM syndrome as well as priorities for ongoing research."}