{"id":"10b3c25ae044","type":"article","url":"https://hartvaat.nl/2026/06/28/cryoballoonablatie-resulteert-in-meer-linkeratrium-uitzetting-dan-radiofrequente/","title":"Cryoballoonablatie resulteert in meer linkeratrium-uitzetting dan radiofrequente ablatie na longaderisolatie","title_en":"Left Atrial Structural and Functional Changes After Pulmonary Vein Isolation Using Different Energy Sources.","category":"atriumfibrilleren","category_label":"Atriumfibrilleren","professions":["cardioloog"],"tags":[],"journal":"Sensors (Basel, Switzerland)","doi":"10.3390/s26134103","source_url":"https://doi.org/10.3390/s26134103","authors":["Jonasz Kozielski","Monika Olczyk","Ewa Świerżyńska-Wodarska","Michał Orczykowski","Bronisław Sulkowski","Łukasz Szumowski","Maciej Sterliński","Marek Szołkiewicz"],"significance":3,"published":"2026-08-03","source_date":"2026-06-28","image":"","kennis":["https://hartvaat.nl/kennis/atriumfibrilleren/elektrisch-remodellering-atrium/"],"congress":"","summary_en":"A prospective study of 42 patients evaluated whether pulmonary vein isolation (PVI) for atrial fibrillation induces different short-term structural and functional changes in the left atrium when using cryoballoon ablation (CBA) versus radiofrequency catheter ablation (RFCA). At 12-month follow-up, the CBA group showed a significantly greater increase in left atrial diameter (p = 0.0017) compared with RFCA, with no significant differences in volumetric indices or mechanical function. Given the small sample size and exploratory nature of the findings, the results do not currently support a change in ablation strategy in routine clinical practice.","created":"2026-07-27T01:31:51Z","updated":"2026-08-10T10:37:18Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Een prospectieve studie van 42 patiënten onderzocht of longaderisolatie (PVI) voor atriumfibrilleren op korte termijn verschillen veroorzaakt in structurele en functionele veranderingen van het linkeratrium tussen cryoballoon- (CBA) en radiofrequente ablatie (RFCA). Na 12 maanden vertoonden patiënten met CBA een significantere toename in linkeratrium-diameter (p = 0,0017) vergeleken met RFCA, zonder significante verschillen in volumetrische indices of mechanische functie. Omdat het onderzoek beperkt is in omvang en als preliminair wordt bestempeld, bieden de resultaten nog geen aanleiding tot aanpassing van de ablatietechniek in de dagelijkse praktijk.","abstract_original":"Background: Pulmonary vein isolation (PVI) is an established treatment for atrial fibrillation (AF); however, its impact on long-term left atrial (LA) structural and mechanical remodeling may differ between ablation techniques. Objectives: The aim of this study is to assess changes in LA structure and function after PVI using cryoballoon ablation (CBA) and radiofrequency catheter ablation (RFCA). Methods: Forty-two patients undergoing PVI were prospectively analyzed (CBA, n = 28; RFCA, n = 14). Transthoracic echocardiography with speckle-tracking analysis was performed before PVI and at 12-month follow-up. LA size, volumetric indices (LAVI), strain components, and functional parameters were assessed. Results: Patients undergoing CBA demonstrated greater increases in selected LA structural parameters during follow-up compared with RFCA. Repeated-measures ANOVA revealed a significant group-by-time interaction for LA diameter (p = 0.0017), while similar trends were observed for LAA (p = 0.0645) and LAS-R (p = 0.0547). No significant interaction effects were observed for LAVI-derived parameters or other indices of LA mechanical function. Conclusions: In this preliminary exploratory study, CBA showed a tendency toward greater structural LA remodeling compared with RFCA during a 12-month follow-up. However, these findings should be interpreted with caution given the limited sample size and population heterogeneity. Larger prospective studies are warranted to validate these observations."}