{"id":"aa7f427c644c","type":"article","url":"https://hartvaat.nl/2026/09/01/verhoogd-10-jaar-ascvd-risico-gekoppeld-aan-linkerventrikelhypertrofie-bij-hyper/","title":"Verhoogd 10-jaar ASCVD-risico gekoppeld aan linkerventrikelhypertrofie bij hypertensiepatiënten","title_en":"Association of 10-year Cardiovascular Risk with Left Ventricular Hypertrophy in a Population of Nigerian Hypertensives.","category":"hypertensie","category_label":"Hypertensie","professions":["cardioloog","huisarts","internist"],"tags":[],"journal":"The Nigerian postgraduate medical journal","doi":"10.4103/npmj.npmj_580_25","source_url":"https://doi.org/10.4103/npmj.npmj_580_25","authors":["Olugbenga Olusola Abiodun","Tina Anya"],"significance":4,"published":"2026-08-27","source_date":"2026-09-01","image":"https://hartvaat.nl/global/img/0155cc89a708.webp","kennis":["https://hartvaat.nl/kennis/hypertensie/hypertensie-en-diabetes/","https://hartvaat.nl/kennis/hypertensie/hypertensie-en-ckd/"],"congress":"","summary_en":"In a cohort of 934 hypertensive patients, an elevated 10-year ASCVD risk score (≥7.5%) was associated with a two-fold higher odds of left ventricular hypertrophy (LVH) on both echocardiography and ECG. Patients with high ASCVD risk had a significantly higher prevalence of LVH compared to those with low risk (42.1% vs 32.3% for echo; 26.3% vs 19.6% for ECG; p < 0.05). These findings suggest that routine ASCVD risk stratification could help identify patients needing timely LVH evaluation, particularly in resource-limited settings.","created":"2026-08-21T00:57:08Z","updated":"2026-08-21T00:57:10Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"In een cohort van 934 hypertensiepatiënten bleek een verhoogd 10-jaar ASCVD-risico (≥7,5%) samen te vallen met een tweevoudig hoger risico op linkerventrikelhypertrofie (LVH), gemeten via echocardiografie of ECG. Patiënten met een hoge risicoscore hadden vaker LVH (42,1% vs 32,3% voor echo; 26,3% vs 19,6% voor ECG; p < 0,05). Deze bevinding ondersteunt het gebruik van de PCE-risicoscore als praktisch hulpmiddel om tijdig doorverwijzingen voor LVH-screening te sturen, met name in instellingen met beperkte middelen.","abstract_original":"BACKGROUND: The pooled cohort equation (PCE) for predicting the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) has been utilised in Black populations to predict cardiovascular events. OBJECTIVE: We explored the relationship between PCE ASCVD risk and left ventricular hypertrophy (LVH). MATERIALS AND METHODS: A total of 934 hypertensives from the Federal Medical Centre Abuja Hypertension Registry were analysed for this study. The participants were divided into two groups: those with low ASCVD risk (<7.5%) and those with elevated ASCVD risk (≥7.5%). Electrocardiographic (ECG) LVH was defined by the presence of any of Sokolow-Lyon, Cornell voltage or Gubner-Ungerleider criteria. Echocardiographic LVH was defined as an elevated LV mass index using the linear cube formula of the American College of Cardiology. RESULTS: Participants with elevated ASCVD risk were older (59.2 ± 9.0 years) than those with low ASCVD risk ( P < 0.001). Among participants with elevated ASCVD risk, 299 (42.1%) and 181 (26.3%) had echocardiographic and ECG LVH compared with 75 (32.3%) and 44 (19.6%) in those with low ASCVD risk, respectively ( P < 0.05). Those with elevated ASCVD risk had higher odds of having echocardiographic (odds ratio [OR]: 2.02, 95% confidence interval CI 1.39-2.93) and ECG LVH (OR: 2.00, 95% CI 1.29-3.08) compared to those in the low-risk group ( P < 0.05). CONCLUSION: In this study, an elevated 10-year ASCVD risk was associated with a two-fold increase in the risk of echocardiographic and ECG LVH in a population of Nigerian hypertensives. In resource-limited settings, the use of the ASCVD risk score may facilitate timely referrals for the diagnosis and management of LVH."}