{"id":"182de30437ea","type":"article","url":"https://hartvaat.nl/2026/10/01/balloon-expandable-tavr-huidige-bewijslast-en-klinische-uitkomsten/","title":"Balloon-expandable TAVR: huidige bewijslast en klinische uitkomsten","title_en":"Balloon-Expandable Transcatheter Aortic Valve Replacement: A Comprehensive Review of Current Evidence and Clinical Outcomes.","category":"algemeen","category_label":"Algemeen","professions":["cardioloog"],"tags":[],"journal":"Interventional cardiology clinics","doi":"10.1016/j.iccl.2026.05.002","source_url":"https://doi.org/10.1016/j.iccl.2026.05.002","authors":["Ahmad Jabri","Luai Madanat","Pedro A Villablanca"],"significance":5,"published":"2026-09-06","source_date":"2026-10-01","image":"","kennis":["https://hartvaat.nl/kennis/kleplijden/aortastenose/","https://hartvaat.nl/kennis/kleplijden/klepprothese-mechanisch-biologisch/"],"congress":"","summary_en":"This comprehensive review traces the evolution of transcatheter aortic valve replacement (TAVR) since 2002, highlighting its expansion from high-risk to low-risk patients with severe aortic stenosis. The authors compare the two main valve platforms—balloon-expandable and self-expanding—and summarise current evidence on clinical outcomes, safety, and procedural considerations. The article provides cardiologists with a practical overview of evolving indications and device selection, supporting informed decision-making in contemporary structural heart disease management.","created":"2026-08-31T00:59:14Z","updated":"2026-08-31T00:59:14Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Deze overzichtsstudie beschrijft de evolutie van transcatheter aortic valve replacement (TAVR) sinds de eerste toepassing in 2002, met een focus op het verschuiven van hoge- naar lage-risicopatiënten met ernstige aortaklepstenose. De auteurs vergelijken de twee belangrijkste klepprothesen (balloon-expandable versus self-expanding) en evalueren de huidige klinische resultaten en veiligheidsprofielen. Het artikel biedt cardiologen een actueel overzicht van de indicatie-expansie en technische verschillen, wat relevant is voor de patiëntselectie en procedurekeuze in de dagelijkse praktijk.","abstract_original":"This article outlines the transformative impact of transcatheter aortic valve replacement (TAVR) since its first successful human use in 2002, redefining the management of severe aortic stenosis. Traditionally treated with surgical aortic valve replacement, many elderly patients with comorbidities were unsuitable for surgery. TAVR has emerged as a less invasive and widely adopted alternative, expanding from high-risk to low-risk populations with strong clinical outcomes. Its rapid global uptake and potential role in earlier intervention highlight its clinical significance. The article also introduces the 2 main valve platforms, balloon-expandable and self-expanding, focusing on their design and evolving applications."}