{"id":"15ead262a965","type":"article","url":"https://hartvaat.nl/2026/10/01/tavr-bij-bicuspidale-aortaklepstenose-veiligheid-en-resultaten-in-de-praktijk/","title":"TAVR bij bicuspidale aortaklepstenose: veiligheid en resultaten in de praktijk","title_en":"Treatment of Bicuspid Aortic Valve Stenosis Using Transcatheter Heart Valves.","category":"algemeen","category_label":"Algemeen","professions":["cardioloog"],"tags":[],"journal":"Interventional cardiology clinics","doi":"10.1016/j.iccl.2026.05.004","source_url":"https://doi.org/10.1016/j.iccl.2026.05.004","authors":["Ahmed A Kolkailah","Pedro Engel Gonzalez"],"significance":3,"published":"2026-09-06","source_date":"2026-10-01","image":"","kennis":["https://hartvaat.nl/kennis/antistolling/doac-versus-vka-keuze/","https://hartvaat.nl/kennis/vasculair/thoracaal-aorta-aneurysma/"],"congress":"","summary_en":"A narrative review addresses the anatomical and clinical challenges of using TAVR in patients with bicuspid aortic valve (BAV) anatomy, who are frequently excluded from pivotal trials. Emerging evidence indicates that TAVR in this population is safe, demonstrates high device success rates, and shows improved procedural outcomes. These findings offer practical guidance for interventional cardiologists on patient selection and technique, though robust randomized data remain limited.","created":"2026-08-31T00:55:58Z","updated":"2026-08-31T00:55:58Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Een narratieve review bespreekt de uitdagingen en anatomische overwegingen bij het toepassen van TAVR bij patiënten met een bicuspidale aortaklep (BAV), die vaak zijn uitgesloten van grotere RCT's. Uit de opkomende evidence blijkt dat de procedure veilig is, het device success hoog is en de uitkomsten verbeterd zijn ten opzichte van eerdere ervaringen. Dit biedt handvatten voor interventiecardiologen bij patiëntselectie en procedurele planning, hoewel robuuste RCT-data nog ontbreken.","abstract_original":"The paucity of data from randomized clinical trials regarding the use of transcatheter aortic valve replacement (TAVR) in bicuspid aortic valve anatomy due to exclusion from pivotal studies continues to present a challenge as we expand TAVR to patients with BAV. This article discusses the important anatomic and clinical considerations in the selection and management of BAV patients with TAVR and reviews the emerging evidence, which increasingly suggests this procedure is safe, device success is excellent, and procedural outcomes are much improved."}