# ESC-consensus richtlijn voor de zorg aan harttransplantatiepatiënten in de reguliere praktijk

*geplaatst 2026-10-27 · Nierziekte · European journal of heart failure · doi 10.1093/ejhf/xuag326 · https://hartvaat.nl/2026/10/19/esc-consensus-richtlijn-voor-de-zorg-aan-harttransplantatiepatienten-in-de-regul/*

Harttransplantatiepatiënten worden steeds vaker behandeld buiten gespecialiseerde centra, maar de zorg blijft complex door immunosuppressie, afstoting en comorbiditeiten. Deze consensusverklaring van de ESC Heart Failure Association en ACNAP biedt een gestructureerd zorgkader voor niet-transplantatiecardiologen en huisartsen, met aandacht voor medicatiemonitoring, infectieprophylaxe, surveillance van allograftvasculopathie en gedeelde zorgmodellen. Het document benadrukt wanneer vroegtijdige verwijzing naar een transplantaatcentrum nodig is en ondersteunt veilige follow-up in de regio.

## English: Management of Heart transplant recipients for the non Heart Transplant health care provider. A Clinical Consensus Statement of the Heart Failure Association (HFA) and the Association of Cardiovascular Nursing & Allied Professions (ACNAP) of the ESC.

The growing number of heart transplant recipients is increasingly managed outside specialized transplant centers, yet post-transplant care remains complex due to immunosuppression, rejection risk, and comorbidities. This ESC consensus statement provides a practical framework for non-specialist cardiologists and primary care physicians, covering immunosuppressive drug monitoring, infection prophylaxis, surveillance for cardiac allograft vasculopathy, and shared-care models. It outlines clear referral criteria to transplant centers and aims to standardize long-term follow-up in routine practice.

## Abstract (original, from the publication)

Heart transplantation (HTx) remains the gold standard treatment for selected patients with advanced heart failure and survival after transplantation has substantially improved over recent decades. As a consequence, the number of long-term HTx recipients continues to increase, and these patients are now frequently encountered in routine practice outside specialized transplant centers. Their management remains complex due to the use of chronic immunosuppression, transplant-specific complications, and a growing burden of comorbidities in the perspective of increasing longevity. Non-transplant cardiologists, general practitioners, and other healthcare professionals are therefore increasingly involved in their care but often have limited experience of post-transplant management. This clinical consensus statement from the Heart Failure Association (HFA) and the Association of Cardiovascular Nursing & Allied Professions (ACNAP) of the ESC provides practical support and a structured framework for healthcare providers involved in the care of HTx recipients outside dedicated transplant centers. The document reviews key aspects of post-transplant management, including outlining principles of care according to time from transplantation, essential knowledge around immunosuppressive therapy and drug monitoring, recognition and initial management of rejection, infection prophylaxis and treatment, and surveillance of long-term complications such as cardiac allograft vasculopathy, malignancy, chronic kidney disease, and metabolic disorders. In addition, specific clinical situations frequently encountered in practice-including fertility and pregnancy, non-cardiac surgery, rehabilitation, and palliative care-are discussed. Particular emphasis is placed on the organization of shared-care models between transplant centers and community providers and on identifying clinical scenarios requiring early referral. Through providing practical recommendations and a structured framework for follow-up, this document aims to support non-specialist clinicians in the safe management of HTx recipients and to facilitate timely collaboration with transplant centers.

Auteurs: Guillaume Baudry, Emer Joyce, Marianna Adamo, Rafaela Batista Dos Santos Pedrosa, Tuvia Ben Gal, Michael Bonios, Maria Generosa Crespo-Leiro, Ida E Hoejskov, Attilio Iacovoni, Chris Kapelios, Hoong Sern Lim, Marco Metra, Felix Schoenrath, Hadi Skouri, Linda W Van Laake, Kevin Damman

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Bron: European journal of heart failure, https://doi.org/10.1093/ejhf/xuag326. Bijgewerkt 2026-10-20T01:13:30Z. Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.