# Incidentie beroerte bij jongvolwassenen stijgt — geassocieerd met hypertensie, diabetes en middelengebruik

*geplaatst 2026-10-02 · Hypertensie · Neurology · doi 10.1212/WNL.0000000000218622 · https://hartvaat.nl/2026/10/27/incidentie-beroerte-bij-jongvolwassenen-stijgt-geassocieerd-met-hypertensie-diab/*

Een populatieonderzoek over bijna dertig jaar toont aan dat de incidentie van beroerte bij jongvolwassenen (20-54 jaar) is gestegen van 33,9 naar 62,2 per 100.000 persoonjaren, voornamelijk door ischemische beroerte. Deze stijging gaat gepaard met een toename van traditionele cardiovasculaire risicofactoren zoals hypertensie, diabetes, atriumfibrilleren en middelengebruik. Hoewel de 30-daagse case fatality rate licht daalde, onderstreept de trend het urgente belang van vroegtijdige risicomanagement en preventie in deze leeftijdsgroep.

## English: Stroke in the Young: Incidence, 30-Day Case Fatality Rates, and Risk Factors Over Time in a Population-Based Study.

A population-based study spanning nearly 30 years reveals that stroke incidence in young adults (20–54 years) has nearly doubled, rising from 33.9 to 62.2 per 100,000 person-years, driven primarily by ischemic stroke. This increase coincides with a marked rise in traditional vascular risk factors, including hypertension, diabetes, atrial fibrillation, and substance use. Although 30-day case fatality rates have modestly declined, the findings underscore the critical need for early cardiovascular risk assessment and prevention strategies in younger populations.

## Abstract (original, from the publication)

BACKGROUND AND OBJECTIVES: Despite an overall decline in incidence rate, the burden of stroke may be rising in young adults. We aimed to characterize the incidence rates, 30-day case fatality rates (CFRs), and the burden of stroke risk factors over time in young adults in a representative population-based study of stroke. METHODS: Using validated methods, hospitalized stroke cases in a 5-county region were ascertained and adjudicated by stroke-trained physicians in 6 study periods: July 1993-June 1994 and calendar years 1999, 2005, 2010, 2015, and 2020. Stroke in the young was defined as those occurring among individuals who were aged 20-54 years. Incidence rates were generated using US Census data standardized to the 2010 population, and trends were tested with linear regression. Temporal trends in 30-day CFR were evaluated with logistic regression after adjusting for age, race, and sex. RESULTS: Across all study periods, there were 2,076 first-ever strokes in young adults. Hypertension, diabetes, atrial fibrillation, and substance use were more common over time (p < 0.001). The stroke incidence rate increased in young adults over time (33.90 cases/100,000 person-years in 1993/4 to 62.18 cases/100,000 person-years in 2020, trend p = 0.04), while declining in older adults (618.78 cases/100,000 person-years in 1993/4 to 453.04 cases/100,000 person-years in 2020, trend p = 0.02). The rise in stroke incidence appeared driven by ischemic stroke, with an almost doubled incidence rate of 23.8 cases/100,000 person-years in 1993/4 to 47.3 cases/100,000 person-years in 2020 (trend p = 0.02). There was a modest decline in the 30-day CFR in young adults (11.7% in 1993/4 to 9.4% in 2020, trend p = 0.002), driven by intracerebral hemorrhage (27.5% in 1993/4 to 21.2% in 2020, trend p = 0.03) and subarachnoid hemorrhage (27.9% in 1993/4 to 18.6% in 2020, trend p = 0.09). DISCUSSION: The incidence of stroke in young adults is rising over time, while the CFR simultaneously declines. This coincides with a rise in both traditional vascular risk factors and substance use.

Auteurs: Emily R Fisher, Lili Ding, Robert J Stanton, Yasmin Ninette Aziz, Stacie Demel, Simona Ferioli, Matthew L Flaherty, Joseph LaPorta, Lauren E Menzies, Eva A Mistry, Paul Wechsler, Kyle B Walsh, Opeolu Adeoye, Elisheva R Coleman, Felipe De Los Rios La Rosa, Adam S Jasne, Pooja Khatri, Jason Mackey, Sharyl R Martini, Lisa Nobel, Sabreena Slavin, Brian Stamm, Michael Star, Daniel Woo, Shea Wright, Joseph P Broderick, Brett Kissela, Dawn Kleindorfer, David Robinson

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Bron: Neurology, https://doi.org/10.1212/WNL.0000000000218622. Bijgewerkt 2026-09-26T00:51:31Z. Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.