# Grote herkenning en controlelekken bij gevorderd cardiovasculair-nier-metabool syndroom

*geplaatst 2026-10-13 · Nierziekte · Preventive medicine reports · doi 10.1016/j.pmedr.2026.103635 · https://hartvaat.nl/2026/11/01/grote-herkenning-en-controlelekken-bij-gevorderd-cardiovasculair-nier-metabool-s/*

Een analyse van NHANES-gegevens (n=5006 volwassenen in de VS) toont dat gevorderd cardiovasculair-nier-metabool (CKM) syndroom (stadia 3-4) voorkomt bij 13,0% van de volwassen bevolking. Van de patiënten met een nierafwijking gaf 80,7% dit niet aan, terwijl 58,7% een bloeddruk ≥130/80 mmHg en 56,0% een HbA1c ≥7% had. Deze nationale cijfers benadrukken de aanzienlijke onderkenning en suboptimale risicofactorencontrole, wat de urgentie van gestructureerde screening en multidisciplinaire cardiorenale zorg in de preventie en huisartspraktijk onderstreept.

## English: Recognition and control gaps in advanced cardiovascular-kidney-metabolic syndrome among United States adults.

A cross-sectional analysis of NHANES data (n=5006 US adults) reveals that advanced cardiovascular-kidney-metabolic (CKM) syndrome (stages 3-4) affects 13.0% of the adult population. Among those with kidney abnormalities, 80.7% did not report it, while 58.7% had uncontrolled blood pressure (≥130/80 mmHg) and 56.0% had suboptimal glycemic control (HbA1c ≥7%). These findings highlight substantial gaps in recognition and risk factor management, underscoring the need for systematic screening and integrated cardiorenal-metabolic care in primary and specialist practice.

## Abstract (original, from the publication)

OBJECTIVE: To describe cardiovascular-kidney-metabolic (CKM) stages and condition-specific indicators among adults in the United States, with exploratory state profiles. METHODS: We analyzed 5006 United States adults aged ≥20 years in the National Health and Nutrition Examination Survey, August 2021-August 2023. Survey weights and condition-specific denominators were used. A stage-3 model developed among adults without reported cardiovascular disease was applied to the 2023 Behavioral Risk Factor Surveillance System. RESULTS: Advanced CKM (stages 3-4) affected 13.0% (95% confidence interval, 11.6%, 14.4%) of adults. Among advanced-CKM adults with a single-visit kidney abnormality, 80.7% did not report weak or failing kidneys. Within applicable subgroups, 58.7% had blood pressure ≥ 130/80 mm Hg and 56.0% had glycated hemoglobin ≥7%. Concurrent elevation affected 34.1% (95% confidence interval, 24.7%, 44.4%) of the fixed hypertension-plus-diabetes subgroup (91/277). Across 49 jurisdictions, the age-standardized modeled stage-3 contribution ranged from 4.4% to 6.5%; directly reported cardiovascular disease was presented separately. CONCLUSIONS: National estimates describe frequent condition-specific abnormalities within advanced CKM, while the separate geographic projections provide exploratory surveillance context. Fixed thresholds do not establish individual treatment failure, and state projections require external validation.

Auteurs: Menghao Zhou, Fen Zhang, Bingluo Zhou, Yiming Lv

---
Bron: Preventive medicine reports, https://doi.org/10.1016/j.pmedr.2026.103635. Bijgewerkt 2026-10-06T01:03:39Z. Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.