{"id":"21679f9c93cb","type":"article","url":"https://hartvaat.nl/2026/12/01/optimale-cardiometabole-gezondheid-tijdens-zwangerschap-verlaagt-risico-op-compl/","title":"Optimale cardiometabole gezondheid tijdens zwangerschap verlaagt risico op complicaties","title_en":"Gestational cardiovascular health and adverse pregnancy outcomes: a prospective cohort study in China.","category":"cholesterol","category_label":"Cholesterol","professions":["huisarts","internist"],"tags":[],"journal":"Annals of medicine","doi":"10.1080/07853890.2026.2703887","source_url":"https://doi.org/10.1080/07853890.2026.2703887","authors":["Qi Wu","Hao Ma","Yihui Wu","Shuqi Zhu","Jiayue Tang","Mengjia Hu","Yibo Tang","Luyao Hu","Lixia Zhang","Xiaolin Xu","Danqing Chen","Lu Qi","Zhaoxia Liang"],"significance":4,"published":"2026-08-17","source_date":"2026-12-01","image":"","kennis":["https://hartvaat.nl/kennis/lipiden/residueel-cardiovasculair-risico/","https://hartvaat.nl/kennis/preventie/risicofactoren-cardiovasculair/"],"congress":"","summary_en":"A prospective cohort study of 2,775 pregnant women in China evaluated the association between gestational cardiovascular health metrics and adverse maternal and neonatal outcomes. Each one-point increase in the composite health score was linked to a 7% lower risk of maternal complications and a 4% lower risk of neonatal complications, with women achieving an ideal score showing 21% and 12% reduced risks, respectively. The findings highlight the potential value of integrating cardiometabolic risk assessment into routine prenatal care to improve short-term pregnancy outcomes and long-term cardiovascular health.","created":"2026-08-11T00:49:05Z","updated":"2026-08-11T00:49:05Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"In een prospectief cohort van 2.775 zwangere vrouwen werd de relatie onderzocht tussen een cardiometabole gezondheidscijfer tijdens de zwangerschap en moeder-kind-complicaties. Elke punt toename in het gezondheidscijfer ging gepaard met een 7% lager risico op moedercomplicaties en een 4% lager risico op neonatale complicaties; vrouwen met een hoog cijfer hadden respectievelijk 21% en 12% minder risico vergeleken met die met een laag cijfer. Deze bevindingen benadrukken het belang van het monitoren van levensstijl- en metabole risicofactoren tijdens de zwangerschap als preventiestrategie voor zowel acute obstetrische als latere cardiometabole aandoeningen.","abstract_original":"BACKGROUND: Pregnancy is regarded as a crucial window period for the assessment and management of cardiovascular health (CVH). This study investigated the relationship between the gestational CVH metrics of Chinese women and adverse pregnancy outcomes. PATIENTS AND METHODS: Six separate CVH metrics (smoking status, body mass index, blood pressure, total cholesterol, fasting blood glucose, and sleep health) were measured at 24-28 gestational weeks and categorized as ideal (2 points), intermediate (1 point), or poor (0 point) to generate a gestational CVH score. Total gestational CVH was categorized as high (all ideal metrics), moderate (no poor metrics), or low (one or more poor metric). Associations between gestational CVH and adverse pregnancy outcomes were evaluated using Poisson regression. RESULTS: Among the 2,775 pregnant women included, 36.07%, 36.11%, and 27.82% had high, moderate, and low CVH, respectively. Each one-point increase in the CVH score was significantly associated with 7% and 4% lower risk of adverse maternal and neonatal outcomes (relative risk [RR], 0.93 and 0.96; 95% confidence interval [CI], 0.90-0.95 and 0.93-0.98). Compared with low CVH, high CVH was associated with 21% and 12% lower risk of adverse maternal and neonatal outcomes (RR, 0.79 and 0.88; 95% CI, 0.72-0.87 and 0.80-0.96). Individual CVH metrics also showed associations with adverse pregnancy outcomes, in which ideal body mass index, fasting blood glucose and sleep health were particularly important. CONCLUSIONS: High gestational CVH was significantly associated with a considerably lower risk of adverse pregnancy outcomes, but approximately two-thirds of pregnant Chinese women do not achieve a high level of CVH."}