{"id":"6318df214e86","type":"article","url":"https://hartvaat.nl/2026/12/01/verhoogde-bloeddruk-bij-jonge-volwassenen-verdubbelt-sterftekans-nhanes-cohort/","title":"Verhoogde bloeddruk bij jonge volwassenen verdubbelt sterftekans — NHANES-cohort","title_en":"Burden of high blood pressure and associated risk for all-cause and cardiovascular mortality among US young adults.","category":"hypertensie","category_label":"Hypertensie","professions":["huisarts","internist"],"tags":[],"journal":"Blood pressure","doi":"10.1080/08037051.2026.2715846","source_url":"https://doi.org/10.1080/08037051.2026.2715846","authors":["Ming Ying","Kunming Bao","Dongjun Bao","Zhiyuan Wu","Junhao He","Zhidong Huang","Lixin Ye","Wenjun Gu"],"significance":4,"published":"2026-08-21","source_date":"2026-12-01","image":"https://hartvaat.nl/global/img/e3f5fb401a32.webp","kennis":["https://hartvaat.nl/kennis/hypertensie/cardiovasculaire-risicoschatting-score2/","https://hartvaat.nl/kennis/hypertensie/hypertensie-en-ckd/"],"congress":"","summary_en":"A cohort analysis of NHANES data (1999–2016) reveals that 23.9% of US young adults (mean age 28.6) have prehypertension and 14.3% have hypertension. Compared with normotensive peers, adjusted hazard ratios for all-cause mortality were 1.82 for prehypertension and 2.39 for hypertension, rising to 4.17 for cardiovascular mortality in those with hypertension. These findings underscore the importance of early blood pressure screening and management in young adults to mitigate long-term mortality risk.","created":"2026-08-15T00:48:16Z","updated":"2026-08-15T00:48:20Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"Een analyse van NHANES-gegevens (1999-2016) toont aan dat bijna een kwart van de Amerikaanse jonge volwassenen (gemiddeld 28 jaar) prehypertensie heeft en 14% hypertensie. In vergelijking met normotensieven was de aangepaste hazard ratio voor sterfte door alle oorzaken 1,82 bij prehypertensie en 2,39 bij hypertensie; voor cardiovasculaire sterfte liep deze op tot 4,17 bij hypertensie. Deze bevindingen benadrukken dat vroegtijdige opsporing en behandeling van een verhoogde bloeddruk in deze leeftijdsgroep essentieel is om de langetermijnsterftekans te beperken.","abstract_original":"Background: High blood pressure (BP) in young adults is an underrecognised public health issue with potential long-term health consequences, including increased mortality risk. To examine the prevalence of prehypertension among US young adults and assess its association with all-cause and cardiovascular mortality. Methods: This cohort study utilised data from the National Health and Nutrition Examination Survey (NHANES) 1999-2016. Cox proportional hazards (PHs) regression models were used to estimate hazard ratios (HRs) for mortality. The Fine and Gray subdistribution hazard model was applied to account for competing risks in cardiovascular mortality. Population attributable fractions (PAFs) were calculated to assess the mortality burden associated with prehypertension and hypertension in this population. Prehypertension was defined as a systolic BP (SBP) of 120-139 mm Hg or a diastolic BP (DBP) of 80-89 mm Hg. All-cause and cardiovascular mortality were ascertained through linkage to the National Death Index (NDI) (up to 2019). Results: Among 18,271 participants (mean [SE] age, 28.6 [0.1] years; 49.6% female), the design-weighted prevalence was 23.9% for prehypertension and 14.3% for hypertension. Compared with normotensive individuals, the adjusted HRs for all-cause mortality were 1.82 (95% CI, 1.20-2.74) for prehypertension and 2.39 (95% CI, 1.50-3.81) for hypertension. The HRs for cardiovascular mortality were 1.37 (95% CI, 0.45-4.15) for prehypertension and 4.17 (95% CI, 1.51-11.51) for hypertension. The PAFs for all-cause mortality were 15.1% for individuals with prehypertension and 16.5% for those with hypertension. For cardiovascular mortality, the PAFs were 6.0% for prehypertension and 36.7% for hypertension. Conclusions: In this nationally representative cohort, prehypertension and hypertension were common among US young adults and associated with increased all-cause mortality. These findings highlight the need for early detection and management of high BP in young adults to reduce mortality risk."}