{"id":"810625634896","type":"article","url":"https://hartvaat.nl/2026/12/31/inter-enkel-bloeddrukverschil-correleert-met-microalbuminurie-bij-hypertensiepat/","title":"Inter-enkel bloeddrukverschil correleert met microalbuminurie bij hypertensiepatiënten","title_en":"Inter-ankle systolic blood pressure difference is associated with microalbuminuria in non-diabetic hypertension patients: A cross-sectional study from two cohorts.","category":"hypertensie","category_label":"Hypertensie","professions":["cardioloog","huisarts","internist"],"tags":[],"journal":"Clinical and experimental hypertension (New York, N.Y. : 1993)","doi":"10.1080/10641963.2026.2712543","source_url":"https://doi.org/10.1080/10641963.2026.2712543","authors":["Yuanyuan Shi","Pengjie Gao","Xingyue Lin","Molei Zhang","Danni Wang","Kamila Kamili","Xiyang Li","Suining Xu","Gang Tian"],"significance":4,"published":"2026-08-17","source_date":"2026-12-31","image":"","kennis":["https://hartvaat.nl/kennis/hypertensie/eindorgaanschade-hypertensie/","https://hartvaat.nl/kennis/nierziekte/diabetische-nefropathie/"],"congress":"","summary_en":"A cross-sectional analysis of 2,500 nondiabetic hypertensive patients found that an inter-ankle systolic blood pressure difference is independently associated with microalbuminuria (UACR > 30 mg/g). Receiver operating characteristic curves demonstrated that this simple physical examination finding effectively identifies subclinical renal damage. The results suggest that measuring ankle blood pressure differences could serve as a practical, low-cost tool for risk stratification and early renal assessment in primary care and cardiology practice.","created":"2026-08-11T00:45:48Z","updated":"2026-08-11T00:45:48Z","licence":"Citeer vrij, met bronvermelding en een link naar hartvaat.nl (de url van het record). Samenvattingen zijn redactioneel werk van HartVaat; de oorspronkelijke publicaties blijven van hun uitgevers (doi). Geen medisch advies.","body_markdown":"In een cross-sectionele studie van 2.500 niet-diabetische hypertensiepatiënten bleek een verschil in systolische bloeddruk tussen beide enkels (sIAND) onafhankelijk geassocieerd te zijn met microalbuminurie (UACR > 30 mg/g). ROC-analyse toonde aan dat dit eenvoudige meetmoment effectief kan helpen bij het opsporen van subklinische nierbeschadiging. Het resultaat biedt huisartsen en cardiologen een laagdrempelige aanwijzing voor risicostratificatie en verdere nefrologische evaluatie bij hypertensie.","abstract_original":"This cross-sectional study aimed to analyze whether inter-ankle systolic blood pressure difference (sIAND) was associated with different stages of hypertensive renal damage. 1,658 and 831 nondiabetic hypertensive patients were included from two cohorts. The hypertensive renal damage was reflected by urinary albumin-to-creatinine ratio (UACR), Cystatin C, and estimated glomerular filtration rate. Logistic regression results showed that sIAND was only associated with subclinical hypertensive renal damage reflected by microalbuminuria (UACR > 30 mg/g) independently. Receiver operating characteristic curves indicated sIAND can identify microalbuminuria more effectively. sIAND can aid in identifying microalbuminuria to provide useful clues for risk stratification and clinical management."}