Nachtelijke hypertensie en prognose bij zeer oude patiënten

Hypertension, Volume 83, Issue 3, Page e25199, March 1, 2026. BACKGROUND:Nocturnal blood pressure (BP) is a better predictor of health outcomes than office or daytime BP. However, the clinical significance of nocturnal hypertension in patients of very advanced age remains unexplored. We aimed to assess the association between nocturnal hypertension and composite cardiovascular outcomes in this population.METHODS:This was a prospective observational study including Japanese elderly outpatients aged ≥80 years. All patients underwent 24-hour ambulatory BP monitoring at baseline. Nocturnal hypertension was defined as nocturnal systolic BP ≥120 mm Hg or diastolic BP≥70 mm Hg. Daytime hypertension was defined as daytime systolic BP ≥135 mm Hg and diastolic BP ≥85 mm Hg. The association between those BP phenotypes and composite cardiovascular outcomes (including fatal and nonfatal cardiovascular disease and all-cause mortality) was examined using Cox regression analysis.RESULTS:A total of 485