Causale claims vereisen gedefinieerde interventies: kanttekening bij CKD-MBD-analyse

The application of the causal method by Magagnoli et al.1 to assess the causal impact of chronic kidney disease–mineral and bone disorder biomarkers on disease progression represents a major methodological step forward, effectively addressing time-varying confounding and selection bias. This effort and the clarity of the study is invaluable for advancing causal inference in nephrology. However, the clinical recommendations—specifically that results “support avoiding and treating hyperphosphatemia .